Total synthesis of isoprostanes via the two-component coupling process

Ana R. Rodríguez, Bernd W. Spur

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

A short total synthesis of isoprostanes has been achieved using a two-component coupling process combined with a diastereoselective protonation under reagent control. The F1-isoprostanes were easily obtained by stereoselective reduction of the C-9 keto group.

Original languageEnglish (US)
Pages (from-to)4575-4579
Number of pages5
JournalTetrahedron Letters
Volume43
Issue number26
DOIs
StatePublished - Jun 28 2002

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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