Abstract
A short total synthesis of isoprostanes has been achieved using a two-component coupling process combined with a diastereoselective protonation under reagent control. The F1-isoprostanes were easily obtained by stereoselective reduction of the C-9 keto group.
Original language | English (US) |
---|---|
Pages (from-to) | 4575-4579 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 43 |
Issue number | 26 |
DOIs | |
State | Published - Jun 28 2002 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry