The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

T. Peter Stein; David Fahrney

doi:10.1039/C19680000555

The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	555-556
Number of pages	2
Journal	Chemical Communications (London)
Issue number	10
DOIs	https://doi.org/10.1039/C19680000555
State	Published - 1968
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Chemistry

Access to Document

10.1039/C19680000555

Cite this

@article{5b794ace9f6143aeaa6d5fc7d6f22fa4,

title = "The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity",

author = "Stein, {T. Peter} and David Fahrney",

note = "Funding Information: We thank Prof. P. D. Boyer for helpful dis- cussions and Miss D. M. Bryan and Mrs. S. Galyean for l80 analyses. This work was supported by a research grant from the United States Public Health Service. (Received, March 25th, 1968; Corn. 371.) T. W. Reid and D. Fahrney, J . Amer. Chem. SOC., 1967, 89, 3941. E. Zeffren and E. T. Kaiser, J . Amer. Chem. SOC., 1967, 89, 4204. K. Inouye and J. Fruton, Biochemistry, 1967, 6, 1765. N. Lutsenko, L. Ginodman, and V. Orekhovich, Biokhimiya, 1967,32, 223. W. T. Jackson, M. Schlamowitz, and A. Shaw, Biochemistry, 1965,4, 1537. R. S. Bayliss and J. R. Knowles, Chem. Comm., 1968, 196. B. F. Erlanger, S. M. Vratsanos, N. Wassermann, and A. G. Cooper, Biochem. Biophys. Res. Comm., 1966,23, 243. ti G. E. Clement and S. L. Snyder, J . Amer. Chem. SOC., 1966, 88, 5338. * T. G. Rajagopalan, W. H. Stein, and S. Moore, J . BioE. Chem., 1966, 241, 4295. lo G. R. Delpierre and J. S. Fruton, Proc. Nut. Acad. Sci. U.S.A., 1966, 56, 1817. l1 E. B. Ong and G. E. Perlmann, Nature, 1967,215, 1492. l2 G. A. Hamilton, J. Spona, and L. D. Crowell, Biochem. Biofihys. Res. Comm., 1967, 26, 193. la V. M. Stepanov and T. I. Vaganova, Bull. Acad. Sci. U.S.S.R., Chem. Ser., 1967, 12, 2785. l4 B. R. Baker, {"}Design of Active-Site-Directed Irreversible Enzyme Inhibitors,'' John Wiley, New York, 1967. l6 P. D. Boyer, D. J. Graves, C. H. Suelter, and M. E. Dempsey, Analyt. Chem., 1961,33, 1906. l6 W. Pryor and N. Tonellato, J . Amer. Chem. SOC., 1967, 89, 3379. l7 J. L. Robinson and P. D. Boyer, personal communication.",

year = "1968",

doi = "10.1039/C19680000555",

language = "English (US)",

pages = "555--556",

journal = "Chemical Communications (London)",

issn = "0009-241X",

publisher = "Royal Society of Chemistry",

number = "10",

}

TY - JOUR

T1 - The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

AU - Stein, T. Peter

AU - Fahrney, David

N1 - Funding Information: We thank Prof. P. D. Boyer for helpful dis- cussions and Miss D. M. Bryan and Mrs. S. Galyean for l80 analyses. This work was supported by a research grant from the United States Public Health Service. (Received, March 25th, 1968; Corn. 371.) T. W. Reid and D. Fahrney, J . Amer. Chem. SOC., 1967, 89, 3941. E. Zeffren and E. T. Kaiser, J . Amer. Chem. SOC., 1967, 89, 4204. K. Inouye and J. Fruton, Biochemistry, 1967, 6, 1765. N. Lutsenko, L. Ginodman, and V. Orekhovich, Biokhimiya, 1967,32, 223. W. T. Jackson, M. Schlamowitz, and A. Shaw, Biochemistry, 1965,4, 1537. R. S. Bayliss and J. R. Knowles, Chem. Comm., 1968, 196. B. F. Erlanger, S. M. Vratsanos, N. Wassermann, and A. G. Cooper, Biochem. Biophys. Res. Comm., 1966,23, 243. ti G. E. Clement and S. L. Snyder, J . Amer. Chem. SOC., 1966, 88, 5338. * T. G. Rajagopalan, W. H. Stein, and S. Moore, J . BioE. Chem., 1966, 241, 4295. lo G. R. Delpierre and J. S. Fruton, Proc. Nut. Acad. Sci. U.S.A., 1966, 56, 1817. l1 E. B. Ong and G. E. Perlmann, Nature, 1967,215, 1492. l2 G. A. Hamilton, J. Spona, and L. D. Crowell, Biochem. Biofihys. Res. Comm., 1967, 26, 193. la V. M. Stepanov and T. I. Vaganova, Bull. Acad. Sci. U.S.S.R., Chem. Ser., 1967, 12, 2785. l4 B. R. Baker, "Design of Active-Site-Directed Irreversible Enzyme Inhibitors,'' John Wiley, New York, 1967. l6 P. D. Boyer, D. J. Graves, C. H. Suelter, and M. E. Dempsey, Analyt. Chem., 1961,33, 1906. l6 W. Pryor and N. Tonellato, J . Amer. Chem. SOC., 1967, 89, 3379. l7 J. L. Robinson and P. D. Boyer, personal communication.

PY - 1968

Y1 - 1968

UR - http://www.scopus.com/inward/record.url?scp=37049139003&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=37049139003&partnerID=8YFLogxK

U2 - 10.1039/C19680000555

DO - 10.1039/C19680000555

M3 - Article

AN - SCOPUS:37049139003

SN - 0009-241X

SP - 555

EP - 556

JO - Chemical Communications (London)

JF - Chemical Communications (London)

IS - 10

ER -

The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Cite this