The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

T. Peter Stein; David Fahrney

doi:10.1039/C19680000555

The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

T. Peter Stein, David Fahrney

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Original language	English (US)
Pages (from-to)	555-556
Number of pages	2
Journal	Chemical Communications (London)
Issue number	10
DOIs	https://doi.org/10.1039/C19680000555
State	Published - 1968

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1039/C19680000555

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@article{5b794ace9f6143aeaa6d5fc7d6f22fa4,

title = "The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity",

author = "Stein, {T. Peter} and David Fahrney",

note = "Funding Information: We thank Prof. P. D. Boyer for helpful dis- cussions and Miss D. M. Bryan and Mrs. S. Galyean for l80 analyses. This work was supported by a research grant from the United States Public Health Service. (Received, March 25th, 1968; Corn. 371.) T. W. Reid and D. Fahrney, J . Amer. Chem. SOC., 1967, 89, 3941. E. Zeffren and E. T. Kaiser, J . Amer. Chem. SOC., 1967, 89, 4204. K. Inouye and J. Fruton, Biochemistry, 1967, 6, 1765. N. Lutsenko, L. Ginodman, and V. Orekhovich, Biokhimiya, 1967,32, 223. W. T. Jackson, M. Schlamowitz, and A. Shaw, Biochemistry, 1965,4, 1537. R. S. Bayliss and J. R. Knowles, Chem. Comm., 1968, 196. B. F. Erlanger, S. M. Vratsanos, N. Wassermann, and A. G. Cooper, Biochem. Biophys. Res. Comm., 1966,23, 243. ti G. E. Clement and S. L. Snyder, J . Amer. Chem. SOC., 1966, 88, 5338. * T. G. Rajagopalan, W. H. Stein, and S. Moore, J . BioE. Chem., 1966, 241, 4295. lo G. R. Delpierre and J. S. Fruton, Proc. Nut. Acad. Sci. U.S.A., 1966, 56, 1817. l1 E. B. Ong and G. E. Perlmann, Nature, 1967,215, 1492. l2 G. A. Hamilton, J. Spona, and L. D. Crowell, Biochem. Biofihys. Res. Comm., 1967, 26, 193. la V. M. Stepanov and T. I. Vaganova, Bull. Acad. Sci. U.S.S.R., Chem. Ser., 1967, 12, 2785. l4 B. R. Baker, {"}Design of Active-Site-Directed Irreversible Enzyme Inhibitors,'' John Wiley, New York, 1967. l6 P. D. Boyer, D. J. Graves, C. H. Suelter, and M. E. Dempsey, Analyt. Chem., 1961,33, 1906. l6 W. Pryor and N. Tonellato, J . Amer. Chem. SOC., 1967, 89, 3379. l7 J. L. Robinson and P. D. Boyer, personal communication. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.",

year = "1968",

doi = "10.1039/C19680000555",

language = "English (US)",

pages = "555--556",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "10",

}

TY - JOUR

T1 - The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

AU - Stein, T. Peter

AU - Fahrney, David

N1 - Funding Information: We thank Prof. P. D. Boyer for helpful dis- cussions and Miss D. M. Bryan and Mrs. S. Galyean for l80 analyses. This work was supported by a research grant from the United States Public Health Service. (Received, March 25th, 1968; Corn. 371.) T. W. Reid and D. Fahrney, J . Amer. Chem. SOC., 1967, 89, 3941. E. Zeffren and E. T. Kaiser, J . Amer. Chem. SOC., 1967, 89, 4204. K. Inouye and J. Fruton, Biochemistry, 1967, 6, 1765. N. Lutsenko, L. Ginodman, and V. Orekhovich, Biokhimiya, 1967,32, 223. W. T. Jackson, M. Schlamowitz, and A. Shaw, Biochemistry, 1965,4, 1537. R. S. Bayliss and J. R. Knowles, Chem. Comm., 1968, 196. B. F. Erlanger, S. M. Vratsanos, N. Wassermann, and A. G. Cooper, Biochem. Biophys. Res. Comm., 1966,23, 243. ti G. E. Clement and S. L. Snyder, J . Amer. Chem. SOC., 1966, 88, 5338. * T. G. Rajagopalan, W. H. Stein, and S. Moore, J . BioE. Chem., 1966, 241, 4295. lo G. R. Delpierre and J. S. Fruton, Proc. Nut. Acad. Sci. U.S.A., 1966, 56, 1817. l1 E. B. Ong and G. E. Perlmann, Nature, 1967,215, 1492. l2 G. A. Hamilton, J. Spona, and L. D. Crowell, Biochem. Biofihys. Res. Comm., 1967, 26, 193. la V. M. Stepanov and T. I. Vaganova, Bull. Acad. Sci. U.S.S.R., Chem. Ser., 1967, 12, 2785. l4 B. R. Baker, "Design of Active-Site-Directed Irreversible Enzyme Inhibitors,'' John Wiley, New York, 1967. l6 P. D. Boyer, D. J. Graves, C. H. Suelter, and M. E. Dempsey, Analyt. Chem., 1961,33, 1906. l6 W. Pryor and N. Tonellato, J . Amer. Chem. SOC., 1967, 89, 3379. l7 J. L. Robinson and P. D. Boyer, personal communication. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.

PY - 1968

Y1 - 1968

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SN - 1359-7345

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ER -

The pepsin-catalysed hydrolysis of sulphite esters. Oxygen-18 studies providing direct evidence for involvement of a carboxyl group in sulphite esterase activity

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