Temporal changes in intracellular free calcium levels in the developing neuroepithelium during neurulation in the chick

Joseph V. Martin, Robert Nagele, Lee Hsin-yi

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Intracellular free calcium ion (Ca2+) levels of the developing chick neuroepithelium during neural tube closure (Hamburger and Hamilton stages 3-11 of embryonic development) were determined using the Hydrophobie acetoxymethyl ester of the fluorescent dye fura-2 (fura-2/AM). Temporal changes in the free Ca2+ level in neuroepithelial cells are correlated with the degree of folding of the neuroepithelium. The concentration of intracellular Ca2+ in the neuroepithelium reaches its highest level when apposing neural folds are actively making contact.

Original languageEnglish (US)
Pages (from-to)655-659
Number of pages5
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume107
Issue number4
DOIs
StatePublished - Jan 1 1994

All Science Journal Classification (ASJC) codes

  • Physiology

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