Temporal changes in intracellular free calcium levels in the developing neuroepithelium during neurulation in the chick

Joseph V. Martin; Robert G. Nagele; Lee Hsin-yi

doi:10.1016/0300-9629(94)90365-4

Temporal changes in intracellular free calcium levels in the developing neuroepithelium during neurulation in the chick

Joseph V. Martin, Robert G. Nagele, Lee Hsin-yi

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Intracellular free calcium ion (Ca²⁺) levels of the developing chick neuroepithelium during neural tube closure (Hamburger and Hamilton stages 3-11 of embryonic development) were determined using the Hydrophobie acetoxymethyl ester of the fluorescent dye fura-2 (fura-2/AM). Temporal changes in the free Ca²⁺ level in neuroepithelial cells are correlated with the degree of folding of the neuroepithelium. The concentration of intracellular Ca²⁺ in the neuroepithelium reaches its highest level when apposing neural folds are actively making contact.

Original language	English (US)
Pages (from-to)	655-659
Number of pages	5
Journal	Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
Volume	107
Issue number	4
DOIs	https://doi.org/10.1016/0300-9629(94)90365-4
State	Published - Apr 1994
Externally published	Yes

All Science Journal Classification (ASJC) codes

Physiology

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10.1016/0300-9629(94)90365-4

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@article{d73379facca249ceb9ea19fdcd880dc3,

title = "Temporal changes in intracellular free calcium levels in the developing neuroepithelium during neurulation in the chick",

abstract = "Intracellular free calcium ion (Ca2+) levels of the developing chick neuroepithelium during neural tube closure (Hamburger and Hamilton stages 3-11 of embryonic development) were determined using the Hydrophobie acetoxymethyl ester of the fluorescent dye fura-2 (fura-2/AM). Temporal changes in the free Ca2+ level in neuroepithelial cells are correlated with the degree of folding of the neuroepithelium. The concentration of intracellular Ca2+ in the neuroepithelium reaches its highest level when apposing neural folds are actively making contact.",

author = "Martin, {Joseph V.} and Nagele, {Robert G.} and Lee Hsin-yi",

note = "Funding Information: Atknowledgements-We thank Donald R. Keir and Matthew W. McConville for their technical assistance. This study was supported by grants from the National Institutes of Health (NS23200) and the Busch Fund of Rutgers Ilniversity.",

year = "1994",

month = apr,

doi = "10.1016/0300-9629(94)90365-4",

language = "English (US)",

volume = "107",

pages = "655--659",

journal = "Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology",

issn = "1095-6433",

publisher = "Elsevier Inc.",

number = "4",

}

Temporal changes in intracellular free calcium levels in the developing neuroepithelium during neurulation in the chick. / Martin, Joseph V.; Nagele, Robert G.; Hsin-yi, Lee.
In: Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology, Vol. 107, No. 4, 04.1994, p. 655-659.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Temporal changes in intracellular free calcium levels in the developing neuroepithelium during neurulation in the chick

AU - Martin, Joseph V.

AU - Nagele, Robert G.

AU - Hsin-yi, Lee

N1 - Funding Information: Atknowledgements-We thank Donald R. Keir and Matthew W. McConville for their technical assistance. This study was supported by grants from the National Institutes of Health (NS23200) and the Busch Fund of Rutgers Ilniversity.

PY - 1994/4

Y1 - 1994/4

N2 - Intracellular free calcium ion (Ca2+) levels of the developing chick neuroepithelium during neural tube closure (Hamburger and Hamilton stages 3-11 of embryonic development) were determined using the Hydrophobie acetoxymethyl ester of the fluorescent dye fura-2 (fura-2/AM). Temporal changes in the free Ca2+ level in neuroepithelial cells are correlated with the degree of folding of the neuroepithelium. The concentration of intracellular Ca2+ in the neuroepithelium reaches its highest level when apposing neural folds are actively making contact.

AB - Intracellular free calcium ion (Ca2+) levels of the developing chick neuroepithelium during neural tube closure (Hamburger and Hamilton stages 3-11 of embryonic development) were determined using the Hydrophobie acetoxymethyl ester of the fluorescent dye fura-2 (fura-2/AM). Temporal changes in the free Ca2+ level in neuroepithelial cells are correlated with the degree of folding of the neuroepithelium. The concentration of intracellular Ca2+ in the neuroepithelium reaches its highest level when apposing neural folds are actively making contact.

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Temporal changes in intracellular free calcium levels in the developing neuroepithelium during neurulation in the chick

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