Synthesis of 2H3-labelled misoprostol and its primary plasma metabolite

Ana Rodríguez; Miguel Nomen; Bernd W. Spur; Jean Jacques Godfroid

doi:10.1002/(SICI)1099-1344(199909)42:9<843::AID-JLCR246>3.0.CO;2-K

Synthesis of ²H₃-labelled misoprostol and its primary plasma metabolite

Ana Rodríguez, Miguel Nomen, Bernd W. Spur, Jean Jacques Godfroid

Cell Biology

Research output: Contribution to journal › Article › peer-review

Abstract

Misoprostol-d₃ (15) and its major plasma metabolite misoprostol free acid-d₃ (5) were synthesized starting from commercially available methyl-d₃-magnesium iodide.

Original language	English (US)
Pages (from-to)	843-850
Number of pages	8
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	42
Issue number	9
DOIs	https://doi.org/10.1002/(SICI)1099-1344(199909)42:9<843::AID-JLCR246>3.0.CO;2-K
State	Published - 1999

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry
Radiology Nuclear Medicine and imaging
Drug Discovery
Spectroscopy
Organic Chemistry

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10.1002/(SICI)1099-1344(199909)42:9<843::AID-JLCR246>3.0.CO;2-K

Cite this

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title = "Synthesis of 2H3-labelled misoprostol and its primary plasma metabolite",

abstract = "Misoprostol-d3 (15) and its major plasma metabolite misoprostol free acid-d3 (5) were synthesized starting from commercially available methyl-d3-magnesium iodide.",

author = "Ana Rodr{\'i}guez and Miguel Nomen and Spur, {Bernd W.} and Godfroid, {Jean Jacques}",

year = "1999",

doi = "10.1002/(SICI)1099-1344(199909)42:9<843::AID-JLCR246>3.0.CO;2-K",

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AU - Nomen, Miguel

AU - Spur, Bernd W.

AU - Godfroid, Jean Jacques

PY - 1999

Y1 - 1999

N2 - Misoprostol-d3 (15) and its major plasma metabolite misoprostol free acid-d3 (5) were synthesized starting from commercially available methyl-d3-magnesium iodide.

AB - Misoprostol-d3 (15) and its major plasma metabolite misoprostol free acid-d3 (5) were synthesized starting from commercially available methyl-d3-magnesium iodide.

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DO - 10.1002/(SICI)1099-1344(199909)42:9<843::AID-JLCR246>3.0.CO;2-K

M3 - Article

AN - SCOPUS:0344172186

SN - 0362-4803

VL - 42

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EP - 850

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

IS - 9

ER -

Synthesis of ²H₃-labelled misoprostol and its primary plasma metabolite

Abstract

All Science Journal Classification (ASJC) codes

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