Synthesis of Leukotriene B3

Bernd Spur, Attilio Crea, Wilfried Peters, Wolfgang König

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

The synthesis of the highly chemotactic leukotriene B3 (1a) and of its 6‐trans isomer 1b by Wittig reaction of the chiral phosphonium salt 3 with the aldehyde 4 is described. A new synthetic route to 4 starting from d‐arabinose is reported.

Original languageEnglish (US)
Pages (from-to)225-228
Number of pages4
JournalArchiv der Pharmazie
Volume318
Issue number3
DOIs
StatePublished - 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science
  • Drug Discovery

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