Successful treatment of Aspergillus prosthetic valve endocarditis with oral voriconazole

Lisa J. Reis, Todd D. Barton, Alberto Pochettino, Omaida Velazquez, Michael McGarvey, Bonnie Milas, Annette Reboli, Mindy G. Schuster

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    21 Scopus citations

    Abstract

    Aspergillus endocarditis is very difficult to cure, even with aggressive surgical debridement and antifungal therapy. Patients with embolie involvement of the central nervous system have an extremely poor prognosis. We describe a patient with prosthetic valve endocarditis due to Aspergillus fumigatus who developed emboli in the brain, eye, and lower extremities. With aggressive surgical debridement of involved sites, aortic valve and root replacement, and long-term therapy with oral voriconazole, he remains without any evidence of infection 2 years later.

    Original languageEnglish (US)
    Pages (from-to)752-753
    Number of pages2
    JournalClinical Infectious Diseases
    Volume41
    Issue number5
    DOIs
    StatePublished - Sep 1 2005

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    All Science Journal Classification (ASJC) codes

    • Microbiology (medical)
    • Infectious Diseases

    Cite this

    Reis, L. J., Barton, T. D., Pochettino, A., Velazquez, O., McGarvey, M., Milas, B., Reboli, A., & Schuster, M. G. (2005). Successful treatment of Aspergillus prosthetic valve endocarditis with oral voriconazole. Clinical Infectious Diseases, 41(5), 752-753. https://doi.org/10.1086/432580