Study on the elution of the adsorbed serum proteins on biphasic calcium phosphate ceramics

Jing Wang; Ying Chen; Xiang Dong Zhu; Yu Jiang Fan; Xing Dong Zhang

doi:10.3724/SP.J.1077.2013.13047

Study on the elution of the adsorbed serum proteins on biphasic calcium phosphate ceramics

Jing Wang, Ying Chen, Xiang Dong Zhu, Yu Jiang Fan, Xing Dong Zhang

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Two types of porous BCP ceramics were fabricated, using human serum as the model of protein solution. The effect of the different eluants and porous structure on the elution of the adsorbed serum proteins on BCP ceramics were investigated. The results showed that 400 mmol/L Na₃PO₄ solution had higher elution efficiency for the adsorbed serum proteins on BCP ceramics than 2 mol/L NaCl or 2% sodium dodecycl sufonate (SDS) solution. Moreover, the porous structure of BCP ceramics had a strong impact on the elution of the adsorbed serum proteins. The microporous structure could promote the adsorption of serum proteins on BCP ceramics and slowed down their release rate, but the 3D interconnected macropores were favorable for the elution and release of serum proteins from the BCP surface.

Original language	English (US)
Pages (from-to)	1143-1147
Number of pages	5
Journal	Wuji Cailiao Xuebao/Journal of Inorganic Materials
Volume	28
Issue number	10
DOIs	https://doi.org/10.3724/SP.J.1077.2013.13047
State	Published - Oct 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Materials Science
Inorganic Chemistry

Access to Document

10.3724/SP.J.1077.2013.13047

Cite this

@article{db3793787cda4238aaf035605790aa6f,

title = "Study on the elution of the adsorbed serum proteins on biphasic calcium phosphate ceramics",

abstract = "Two types of porous BCP ceramics were fabricated, using human serum as the model of protein solution. The effect of the different eluants and porous structure on the elution of the adsorbed serum proteins on BCP ceramics were investigated. The results showed that 400 mmol/L Na3PO4 solution had higher elution efficiency for the adsorbed serum proteins on BCP ceramics than 2 mol/L NaCl or 2% sodium dodecycl sufonate (SDS) solution. Moreover, the porous structure of BCP ceramics had a strong impact on the elution of the adsorbed serum proteins. The microporous structure could promote the adsorption of serum proteins on BCP ceramics and slowed down their release rate, but the 3D interconnected macropores were favorable for the elution and release of serum proteins from the BCP surface.",

author = "Jing Wang and Ying Chen and Zhu, {Xiang Dong} and Fan, {Yu Jiang} and Zhang, {Xing Dong}",

year = "2013",

month = oct,

doi = "10.3724/SP.J.1077.2013.13047",

language = "English (US)",

volume = "28",

pages = "1143--1147",

journal = "Wuji Cailiao Xuebao/Journal of Inorganic Materials",

issn = "1000-324X",

publisher = "Science Press",

number = "10",

}

TY - JOUR

T1 - Study on the elution of the adsorbed serum proteins on biphasic calcium phosphate ceramics

AU - Wang, Jing

AU - Chen, Ying

AU - Zhu, Xiang Dong

AU - Fan, Yu Jiang

AU - Zhang, Xing Dong

PY - 2013/10

Y1 - 2013/10

N2 - Two types of porous BCP ceramics were fabricated, using human serum as the model of protein solution. The effect of the different eluants and porous structure on the elution of the adsorbed serum proteins on BCP ceramics were investigated. The results showed that 400 mmol/L Na3PO4 solution had higher elution efficiency for the adsorbed serum proteins on BCP ceramics than 2 mol/L NaCl or 2% sodium dodecycl sufonate (SDS) solution. Moreover, the porous structure of BCP ceramics had a strong impact on the elution of the adsorbed serum proteins. The microporous structure could promote the adsorption of serum proteins on BCP ceramics and slowed down their release rate, but the 3D interconnected macropores were favorable for the elution and release of serum proteins from the BCP surface.

AB - Two types of porous BCP ceramics were fabricated, using human serum as the model of protein solution. The effect of the different eluants and porous structure on the elution of the adsorbed serum proteins on BCP ceramics were investigated. The results showed that 400 mmol/L Na3PO4 solution had higher elution efficiency for the adsorbed serum proteins on BCP ceramics than 2 mol/L NaCl or 2% sodium dodecycl sufonate (SDS) solution. Moreover, the porous structure of BCP ceramics had a strong impact on the elution of the adsorbed serum proteins. The microporous structure could promote the adsorption of serum proteins on BCP ceramics and slowed down their release rate, but the 3D interconnected macropores were favorable for the elution and release of serum proteins from the BCP surface.

UR - http://www.scopus.com/inward/record.url?scp=84889058422&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889058422&partnerID=8YFLogxK

U2 - 10.3724/SP.J.1077.2013.13047

DO - 10.3724/SP.J.1077.2013.13047

M3 - Article

AN - SCOPUS:84889058422

SN - 1000-324X

VL - 28

SP - 1143

EP - 1147

JO - Wuji Cailiao Xuebao/Journal of Inorganic Materials

JF - Wuji Cailiao Xuebao/Journal of Inorganic Materials

IS - 10

ER -

Study on the elution of the adsorbed serum proteins on biphasic calcium phosphate ceramics

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this