Single-Molecule Approaches Reveal the Idiosyncrasies of RNA Polymerases

Jordanka Zlatanova, William T. McAllister, Sergei Borukhov, Sanford H. Leuba

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Recently developed single-molecule techniques have provided new insights into the function of one of the most complex and highly regulated processes in the cell-the transcription of the DNA template into RNA. This review discusses methods and results from this emerging field, and it puts them in perspective of existing biochemical and structural data.

Original languageEnglish (US)
Pages (from-to)953-966
Number of pages14
Issue number6
StatePublished - Jun 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology


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