TY - GEN
T1 - Robustness of inverse perturbation for discrete event control
AU - Bouaynaya, Nidhal
AU - Shterenberg, Roman
AU - Schonfeld, Dan
PY - 2011
Y1 - 2011
N2 - We study the robustness of the inverse perturbation solution in discrete-time systems modeled by homogeneous Markov chains. We cast the optimal inverse perturbation control as a strictly convex optimization problem, which admits a unique global solution. We show that the optimal inverse perturbation control is robust to estimation errors in the original network. The derived results are applied to the Human melanoma gene regulatory network, where the aim is to force the network to converge to a desired steady-state distribution of gene regulation.
AB - We study the robustness of the inverse perturbation solution in discrete-time systems modeled by homogeneous Markov chains. We cast the optimal inverse perturbation control as a strictly convex optimization problem, which admits a unique global solution. We show that the optimal inverse perturbation control is robust to estimation errors in the original network. The derived results are applied to the Human melanoma gene regulatory network, where the aim is to force the network to converge to a desired steady-state distribution of gene regulation.
UR - http://www.scopus.com/inward/record.url?scp=84862240356&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862240356&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2011.6090674
DO - 10.1109/IEMBS.2011.6090674
M3 - Conference contribution
C2 - 22254830
AN - SCOPUS:84862240356
SN - 9781424441211
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 2422
EP - 2425
BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Y2 - 30 August 2011 through 3 September 2011
ER -