TY - JOUR
T1 - Review—Micro-Fuel Cell Principal Biosensors for Monitoring Transdermal Volatile Organic Compounds in Humans
AU - Benhaddouch, Tinsley Elizabeth
AU - Pinzon, Sofia Kelsey
AU - Landi, Diego Magalhaes Castro
AU - Marcial, John
AU - Mehta, Prateek
AU - Romero, Karen
AU - Rockward, Tommy
AU - Bhansali, Shekhar
AU - Dong, Dongmei
N1 - Publisher Copyright:
© 2022 The Author(s). Published on behalf of The Electrochemical Society by IOP Publishing Limited.
PY - 2022/12/1
Y1 - 2022/12/1
N2 - Knowledge of transduction mechanisms in biosensing applications paves the way for ultrasensitive and dynamic detection in living systems. Real-world biosensing applications where ultra-sensitivity and dynamic detection are paramount include monitoring the anesthetic agent concentration during surgery; the slightest variation in concentration can potentially result in a life-threatening overdose or, on the other end of the spectrum, the patient’s awareness during the procedure. We review the benefits and functions of the transcutaneous biosensor device compared with other current technology and discuss the sensor’s capability to accurately measure volatile anesthetic gas concentration in blood using fuel cell technology. We review fundamental concepts of fuel-cell technology for wearable bio-sensing applications. The fuel cell sensor can also continuously monitor other volatile organic compounds making it versatile with numerous potential applications.
AB - Knowledge of transduction mechanisms in biosensing applications paves the way for ultrasensitive and dynamic detection in living systems. Real-world biosensing applications where ultra-sensitivity and dynamic detection are paramount include monitoring the anesthetic agent concentration during surgery; the slightest variation in concentration can potentially result in a life-threatening overdose or, on the other end of the spectrum, the patient’s awareness during the procedure. We review the benefits and functions of the transcutaneous biosensor device compared with other current technology and discuss the sensor’s capability to accurately measure volatile anesthetic gas concentration in blood using fuel cell technology. We review fundamental concepts of fuel-cell technology for wearable bio-sensing applications. The fuel cell sensor can also continuously monitor other volatile organic compounds making it versatile with numerous potential applications.
UR - http://www.scopus.com/inward/record.url?scp=85147648592&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85147648592&partnerID=8YFLogxK
U2 - 10.1149/2754-2726/aca95b
DO - 10.1149/2754-2726/aca95b
M3 - Review article
AN - SCOPUS:85147648592
SN - 2754-2726
VL - 1
JO - ECS Sensors Plus
JF - ECS Sensors Plus
IS - 4
M1 - 041602
ER -