To study the major histocompatibility complex class II I-E dependence of mouse mammary tumor virus (MMTV) superantigens, we constructed hybrids between the I-E-dependent MMTV(GR) and the I-E-independent mtv-7 superantigens and tested them in vivo. Our results suggest that, although the C-terminal third mediates I-A interaction, additional binding sites are located elsewhere in the superantigen.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of virology|
|State||Published - Nov 2002|
All Science Journal Classification (ASJC) codes
- Insect Science