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Postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia

Research output: Contribution to journalArticlepeer-review

Abstract

Exposure to hyperoxia, invasive mechanical ventilation, and systemic/local sepsis are important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia (BPD). This review will summarize information obtained from animal (baboon, lamb/sheep, rat and mouse) models that pertain to the specific inflammatory agents and signaling molecules that predispose a premature infant to BPD.

Original languageEnglish (US)
Pages (from-to)189-201
Number of pages13
JournalBirth Defects Research Part A - Clinical and Molecular Teratology
Volume100
Issue number3
DOIs
StatePublished - Mar 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Developmental Biology

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