Poly (ionic liquid) surgical and tissue adhesive

Iman Noshadi (Inventor)

Research output: Innnovationinnovation

Abstract

Technology

This is a new method to improve the adhesion properties of any biomaterial. This method is very general and applicable with wide range of materials. This method is simple and easy to use. Dr. Iman Noshadi in the Department of Chemical Engineering has developed a modified hydrogel to make antimicrobial, highly adhesive for surgical applications. This application details the engineering of a new class of electroconductive hydrogels (ECHs) through the functionalization of non-conductive polymers with a conductive choline-based bio-ionic liquid (Bio-IL). These conjugated hydrogels exhibited a wide range of adaptable physical properties, biocompatibility, and high electrical conductivity. These ECHs comprise a potential new class of biomaterials that combine electrical properties with biocompatible materials thus opening up the possibility of a new generation of smart materials for use in such things as medical devices. Previous work has shown this material could support the growth and function of cardiomyocytes, can be efficiently biodegraded, and possess low immunogenicity when implanted in rats.

 

Potential Application

Hydrogels have a variety of used in the treatment of wounds and surgical sites. Hydrogels are inherently moist thus facilitating the healing process, can be packed into the wound spaces, and can be engineered to deliver antimicrobial molecules and other drugs.

 

Opportunity

The global sealants and adhesives is estimated at USD 1.8 billion in 2015 and projected the market to grow at a CAGR of 9.7%. Globally the amount of surgeries has increased thus leading to increased product demand. According to the WHO approximately 235 million major surgical procedures are undertaken worldwide every year. Surgical procedures are normally accompanied by risk of wound infection, excessive bleeding, or tissue damage thus fueling the need for effective tissue sealants and adhesives. Rowan University is looking for a partner for further development and commercialization of this technology through a license.

Original languageEnglish (US)
StatePublished - Oct 2018

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Tissue Adhesives
Ionic Liquids
Hydrogels
Biocompatible Materials
Adhesives
Sorbus
Chemical Engineering
Technology Transfer
Electric Conductivity
Hydrogel
Wound Infection
Licensure
Choline
Cardiac Myocytes
Polymers
Hemorrhage
Equipment and Supplies
Wounds and Injuries
Growth
Pharmaceutical Preparations

Cite this

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abstract = "TechnologyThis is a new method to improve the adhesion properties of any biomaterial. This method is very general and applicable with wide range of materials. This method is simple and easy to use. Dr. Iman Noshadi in the Department of Chemical Engineering has developed a modified hydrogel to make antimicrobial, highly adhesive for surgical applications. This application details the engineering of a new class of electroconductive hydrogels (ECHs) through the functionalization of non-conductive polymers with a conductive choline-based bio-ionic liquid (Bio-IL). These conjugated hydrogels exhibited a wide range of adaptable physical properties, biocompatibility, and high electrical conductivity. These ECHs comprise a potential new class of biomaterials that combine electrical properties with biocompatible materials thus opening up the possibility of a new generation of smart materials for use in such things as medical devices. Previous work has shown this material could support the growth and function of cardiomyocytes, can be efficiently biodegraded, and possess low immunogenicity when implanted in rats. Potential ApplicationHydrogels have a variety of used in the treatment of wounds and surgical sites. Hydrogels are inherently moist thus facilitating the healing process, can be packed into the wound spaces, and can be engineered to deliver antimicrobial molecules and other drugs. OpportunityThe global sealants and adhesives is estimated at USD 1.8 billion in 2015 and projected the market to grow at a CAGR of 9.7{\%}. Globally the amount of surgeries has increased thus leading to increased product demand. According to the WHO approximately 235 million major surgical procedures are undertaken worldwide every year. Surgical procedures are normally accompanied by risk of wound infection, excessive bleeding, or tissue damage thus fueling the need for effective tissue sealants and adhesives. Rowan University is looking for a partner for further development and commercialization of this technology through a license.",
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N2 - TechnologyThis is a new method to improve the adhesion properties of any biomaterial. This method is very general and applicable with wide range of materials. This method is simple and easy to use. Dr. Iman Noshadi in the Department of Chemical Engineering has developed a modified hydrogel to make antimicrobial, highly adhesive for surgical applications. This application details the engineering of a new class of electroconductive hydrogels (ECHs) through the functionalization of non-conductive polymers with a conductive choline-based bio-ionic liquid (Bio-IL). These conjugated hydrogels exhibited a wide range of adaptable physical properties, biocompatibility, and high electrical conductivity. These ECHs comprise a potential new class of biomaterials that combine electrical properties with biocompatible materials thus opening up the possibility of a new generation of smart materials for use in such things as medical devices. Previous work has shown this material could support the growth and function of cardiomyocytes, can be efficiently biodegraded, and possess low immunogenicity when implanted in rats. Potential ApplicationHydrogels have a variety of used in the treatment of wounds and surgical sites. Hydrogels are inherently moist thus facilitating the healing process, can be packed into the wound spaces, and can be engineered to deliver antimicrobial molecules and other drugs. OpportunityThe global sealants and adhesives is estimated at USD 1.8 billion in 2015 and projected the market to grow at a CAGR of 9.7%. Globally the amount of surgeries has increased thus leading to increased product demand. According to the WHO approximately 235 million major surgical procedures are undertaken worldwide every year. Surgical procedures are normally accompanied by risk of wound infection, excessive bleeding, or tissue damage thus fueling the need for effective tissue sealants and adhesives. Rowan University is looking for a partner for further development and commercialization of this technology through a license.

AB - TechnologyThis is a new method to improve the adhesion properties of any biomaterial. This method is very general and applicable with wide range of materials. This method is simple and easy to use. Dr. Iman Noshadi in the Department of Chemical Engineering has developed a modified hydrogel to make antimicrobial, highly adhesive for surgical applications. This application details the engineering of a new class of electroconductive hydrogels (ECHs) through the functionalization of non-conductive polymers with a conductive choline-based bio-ionic liquid (Bio-IL). These conjugated hydrogels exhibited a wide range of adaptable physical properties, biocompatibility, and high electrical conductivity. These ECHs comprise a potential new class of biomaterials that combine electrical properties with biocompatible materials thus opening up the possibility of a new generation of smart materials for use in such things as medical devices. Previous work has shown this material could support the growth and function of cardiomyocytes, can be efficiently biodegraded, and possess low immunogenicity when implanted in rats. Potential ApplicationHydrogels have a variety of used in the treatment of wounds and surgical sites. Hydrogels are inherently moist thus facilitating the healing process, can be packed into the wound spaces, and can be engineered to deliver antimicrobial molecules and other drugs. OpportunityThe global sealants and adhesives is estimated at USD 1.8 billion in 2015 and projected the market to grow at a CAGR of 9.7%. Globally the amount of surgeries has increased thus leading to increased product demand. According to the WHO approximately 235 million major surgical procedures are undertaken worldwide every year. Surgical procedures are normally accompanied by risk of wound infection, excessive bleeding, or tissue damage thus fueling the need for effective tissue sealants and adhesives. Rowan University is looking for a partner for further development and commercialization of this technology through a license.

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