Neuropsychiatric symptoms and medical illness in patients with dementia: An exploratory study

Peter Tran, Kara Schmidt, Jennifer Gallo, Ehab Tuppo, Stephen Scheinthal, Anita Chopra, David J. Libon

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Objective: To determine the association between neuropsychiatric symptoms and the presence of medical illness among outpatients with mild dementia. Method: The Neuropsychiatric Inventory (NPI) was used to assess neuropsychiatric symptoms, and the Cumulative Illness Rating Scale (CIRS) was used to evaluate physical impairment, in 44 outpatients diagnosed as having dementia (Alzheimer disease, n=22; vascular dementia, n=13; mixed dementia, n=9). The tests used were standard parts of a memory assessment program at a college of osteopathic medicine. Pearson product moment correlations were used to assess any associations between NPI and CIRS scores. Results: Significant associations were identified between several NPI-assessed symptoms and degree of medical illness as measured by the CIRS. Neurobehavioral problems were significantly correlated (P<.05) with illness in the following body organ systems: gastrointestinal (lower), genitourinary, neurologic, ophthalmologic/otolaryngologic, psychiatric, and respiratory. Conclusion: The authors' preliminary data underscore the importance of primary care physicians assessing patients with dementia for comorbidity of psychiatric illnesses when conducting medical examinations.

Original languageEnglish (US)
Pages (from-to)412-414
Number of pages3
JournalJournal of the American Osteopathic Association
Volume106
Issue number7
StatePublished - Aug 25 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Complementary and alternative medicine

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