Abstract
We localized five rpoC (β') mutations affecting Escherichia coli RNA polymerase assembly. The Ts4, XH56, and R120 mutations changed β' residues conserved throughout eubacteria; the JE10092 mutation occurred in the hypervariable region; rpoC1 (TsX) changed a universally conserved residue and corresponds to yeast rpbl-1. Thus, distinct, predominantly conserved β' residues participate in interactions holding RNA polymerase together.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2663-2665 |
| Number of pages | 3 |
| Journal | Journal of bacteriology |
| Volume | 181 |
| Issue number | 8 |
| DOIs | |
| State | Published - Apr 1999 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Microbiology
- Molecular Biology
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