TY - JOUR
T1 - Localization of Escherichia coli rpoC mutations that affect RNA polymerase assembly and activity at high temperature
AU - Nedea, Eduard C.
AU - Markov, Dmitriy
AU - Naryshkina, Tatyana
AU - Severinov, Konstantin
PY - 1999/4
Y1 - 1999/4
N2 - We localized five rpoC (β') mutations affecting Escherichia coli RNA polymerase assembly. The Ts4, XH56, and R120 mutations changed β' residues conserved throughout eubacteria; the JE10092 mutation occurred in the hypervariable region; rpoC1 (TsX) changed a universally conserved residue and corresponds to yeast rpbl-1. Thus, distinct, predominantly conserved β' residues participate in interactions holding RNA polymerase together.
AB - We localized five rpoC (β') mutations affecting Escherichia coli RNA polymerase assembly. The Ts4, XH56, and R120 mutations changed β' residues conserved throughout eubacteria; the JE10092 mutation occurred in the hypervariable region; rpoC1 (TsX) changed a universally conserved residue and corresponds to yeast rpbl-1. Thus, distinct, predominantly conserved β' residues participate in interactions holding RNA polymerase together.
UR - http://www.scopus.com/inward/record.url?scp=0032907144&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032907144&partnerID=8YFLogxK
U2 - 10.1128/jb.181.8.2663-2665.1999
DO - 10.1128/jb.181.8.2663-2665.1999
M3 - Article
C2 - 10198039
AN - SCOPUS:0032907144
SN - 0021-9193
VL - 181
SP - 2663
EP - 2665
JO - Journal of bacteriology
JF - Journal of bacteriology
IS - 8
ER -