Kokum (Garcinol)

Manoj K. Pandey; Ajaikumar B. Kunnumakkara; Bharat B. Aggarwal

doi:10.1142/9789812837912_0011

Kokum (Garcinol)

Manoj K. Pandey, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

Kokum, a spice derived from fruit of the Garcinia indica tree, is traditionally used in Ayurvedic medicine to facilitate digestion and to treat sores, dermatitis, diarrhea, dysentery, and ear infection. One of the major active components of kokum is garcinol, a polyisoprenylated benzophenone active against bacteria, viruses, gastric ulcers, and cancers. Garcinol's antiproliferative, antibacterial, antioxidant and anti-inflammatory effects result from its modulation of numerous cell-signaling intermediates. This chapter discusses the sources, chemical components, mechanism of action, and disease targets of the kokum spice.

Original language	English (US)
Title of host publication	Molecular Targets and Therapeutic Uses of Spices
Subtitle of host publication	Modern Uses for Ancient Medicine
Publisher	World Scientific Publishing Co.
Pages	281-310
Number of pages	30
ISBN (Electronic)	9789812837912
ISBN (Print)	9812837906, 9789812837905
DOIs	https://doi.org/10.1142/9789812837912_0011
State	Published - Jan 1 2009
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Agricultural and Biological Sciences
General Engineering
General Medicine

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10.1142/9789812837912_0011

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AU - Kunnumakkara, Ajaikumar B.

AU - Aggarwal, Bharat B.

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AB - Kokum, a spice derived from fruit of the Garcinia indica tree, is traditionally used in Ayurvedic medicine to facilitate digestion and to treat sores, dermatitis, diarrhea, dysentery, and ear infection. One of the major active components of kokum is garcinol, a polyisoprenylated benzophenone active against bacteria, viruses, gastric ulcers, and cancers. Garcinol's antiproliferative, antibacterial, antioxidant and anti-inflammatory effects result from its modulation of numerous cell-signaling intermediates. This chapter discusses the sources, chemical components, mechanism of action, and disease targets of the kokum spice.

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M3 - Chapter

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BT - Molecular Targets and Therapeutic Uses of Spices

PB - World Scientific Publishing Co.

ER -

Kokum (Garcinol)

Abstract

All Science Journal Classification (ASJC) codes

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