Kokum (Garcinol)

Manoj Pandey, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Kokum, a spice derived from fruit of the Garcinia indica tree, is traditionally used in Ayurvedic medicine to facilitate digestion and to treat sores, dermatitis, diarrhea, dysentery, and ear infection. One of the major active components of kokum is garcinol, a polyisoprenylated benzophenone active against bacteria, viruses, gastric ulcers, and cancers. Garcinol's antiproliferative, antibacterial, antioxidant and anti-inflammatory effects result from its modulation of numerous cell-signaling intermediates. This chapter discusses the sources, chemical components, mechanism of action, and disease targets of the kokum spice.

Original languageEnglish (US)
Title of host publicationMolecular Targets and Therapeutic Uses of Spices
Subtitle of host publicationModern Uses for Ancient Medicine
PublisherWorld Scientific Publishing Co.
Pages281-310
Number of pages30
ISBN (Electronic)9789812837912
ISBN (Print)9812837906, 9789812837905
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences(all)
  • Engineering(all)
  • Medicine(all)

Cite this

Pandey, M., Kunnumakkara, A. B., & Aggarwal, B. B. (2009). Kokum (Garcinol). In Molecular Targets and Therapeutic Uses of Spices: Modern Uses for Ancient Medicine (pp. 281-310). World Scientific Publishing Co.. https://doi.org/10.1142/9789812837912_0011