Intracellular pH-induced fluorescence used to track nanoparticles in cells

F. R. Cheng, Y. Chen, T. Su, H. Cao, S. Li, J. Cao, B. He, Z. W. Gu, X. L. Luo

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A nanoparticle with pH-induced fluorescence was reported for intracellular tracking. The fluorescence was evoked by the isomerization of the ring-closed form spiropyran (SP) to the ring-open form merocyanine (MC) in the weak acidic environment of cells. The SP-MC switch accelerated the dissociation of nanoparticles to trigger the release of trapped paclitaxel.

Original languageEnglish (US)
Pages (from-to)5411-5414
Number of pages4
JournalJournal of Materials Chemistry B
Volume3
Issue number27
DOIs
StatePublished - Jul 21 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Biomedical Engineering
  • General Materials Science

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