Intracellular pH-induced fluorescence used to track nanoparticles in cells

F. R. Cheng; Y. Chen; T. Su; H. Cao; S. Li; J. Cao; B. He; Z. W. Gu; X. L. Luo

doi:10.1039/c5tb00756a

Intracellular pH-induced fluorescence used to track nanoparticles in cells

F. R. Cheng, Y. Chen, T. Su, H. Cao, S. Li, J. Cao, B. He, Z. W. Gu, X. L. Luo

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A nanoparticle with pH-induced fluorescence was reported for intracellular tracking. The fluorescence was evoked by the isomerization of the ring-closed form spiropyran (SP) to the ring-open form merocyanine (MC) in the weak acidic environment of cells. The SP-MC switch accelerated the dissociation of nanoparticles to trigger the release of trapped paclitaxel.

Original language	English (US)
Pages (from-to)	5411-5414
Number of pages	4
Journal	Journal of Materials Chemistry B
Volume	3
Issue number	27
DOIs	https://doi.org/10.1039/c5tb00756a
State	Published - Jul 21 2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Chemistry
Biomedical Engineering
General Materials Science

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10.1039/c5tb00756a

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abstract = "A nanoparticle with pH-induced fluorescence was reported for intracellular tracking. The fluorescence was evoked by the isomerization of the ring-closed form spiropyran (SP) to the ring-open form merocyanine (MC) in the weak acidic environment of cells. The SP-MC switch accelerated the dissociation of nanoparticles to trigger the release of trapped paclitaxel.",

author = "Cheng, {F. R.} and Y. Chen and T. Su and H. Cao and S. Li and J. Cao and B. He and Gu, {Z. W.} and Luo, {X. L.}",

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T1 - Intracellular pH-induced fluorescence used to track nanoparticles in cells

AU - Cheng, F. R.

AU - Chen, Y.

AU - Su, T.

AU - Cao, H.

AU - Li, S.

AU - Cao, J.

AU - He, B.

AU - Gu, Z. W.

AU - Luo, X. L.

PY - 2015/7/21

Y1 - 2015/7/21

N2 - A nanoparticle with pH-induced fluorescence was reported for intracellular tracking. The fluorescence was evoked by the isomerization of the ring-closed form spiropyran (SP) to the ring-open form merocyanine (MC) in the weak acidic environment of cells. The SP-MC switch accelerated the dissociation of nanoparticles to trigger the release of trapped paclitaxel.

AB - A nanoparticle with pH-induced fluorescence was reported for intracellular tracking. The fluorescence was evoked by the isomerization of the ring-closed form spiropyran (SP) to the ring-open form merocyanine (MC) in the weak acidic environment of cells. The SP-MC switch accelerated the dissociation of nanoparticles to trigger the release of trapped paclitaxel.

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JF - Journal of Materials Chemistry B

IS - 27

ER -

Intracellular pH-induced fluorescence used to track nanoparticles in cells

Abstract

All Science Journal Classification (ASJC) codes

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