Abstract
The interferon-specific cellular receptors in human cells cultures differing in sensitivity to alpha-interferon have been studied. The J-41 cells resistant to alpha-interferon are practically devoid of receptors highly specific to alpha-interferon. The coefficient of equilibrium and the number of receptors analyzed after Scatchard for J-96 culture of cells are 15.6 x 10(11) M-1 and 210 +/- 90, respectively. Evidently, resistance of J-41 cells to alpha-interferon is connected with the absence of interferon receptors and, as a consequence, inability to interferon-receptor interaction.
Translated title of the contribution | Interferon-specific cellular receptors in cultured human cells, differing in sensitivity to alpha-interferon |
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Original language | Russian |
Pages (from-to) | 38-41 |
Number of pages | 4 |
Journal | Molekuliarnaia genetika, mikrobiologiia i virusologiia |
Issue number | 7 |
State | Published - Jul 1989 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- General Medicine