Interferon-spetsificheskie kletochnye retseptory v kul'turakh chelovecheskikh kletok, razlichaiushchikhsiia po chuvstvitel'nosti k alpha-interferonu.

Translated title of the contribution: Interferon-specific cellular receptors in cultured human cells, differing in sensitivity to alpha-interferon

A. N. Narovlianskiǐ, A. M. Amchenkova, S. I. Borukhov, E. G. Alimov, A. I. Strongin, I. E. Khesin

Research output: Contribution to journalArticlepeer-review

Abstract

The interferon-specific cellular receptors in human cells cultures differing in sensitivity to alpha-interferon have been studied. The J-41 cells resistant to alpha-interferon are practically devoid of receptors highly specific to alpha-interferon. The coefficient of equilibrium and the number of receptors analyzed after Scatchard for J-96 culture of cells are 15.6 x 10(11) M-1 and 210 +/- 90, respectively. Evidently, resistance of J-41 cells to alpha-interferon is connected with the absence of interferon receptors and, as a consequence, inability to interferon-receptor interaction.

Translated title of the contributionInterferon-specific cellular receptors in cultured human cells, differing in sensitivity to alpha-interferon
Original languageRussian
Pages (from-to)38-41
Number of pages4
JournalMolekuliarnaia genetika, mikrobiologiia i virusologiia
Issue number7
StatePublished - Jul 1 1989
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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