TY - JOUR
T1 - Integrating CRISPR-Cas9 technology into undergraduate courses
T2 - Perspectives from a National Science Foundation (NSF) workshop for undergraduate faculty, June 2018
AU - Wolyniak, Michael J.
AU - Austin, Shane
AU - Bloodworth, Lucian F.
AU - Carter, Dawn
AU - Harrison, Scott H.
AU - Hoage, Tiffany
AU - Hollis-Brown, Lisa
AU - Jefferson, Felicia
AU - Krufka, Alison
AU - Safadi-Chamberlin, Farida
AU - Santisteban, Maria S.
AU - Soneral, Paula
AU - Van Winkle, Beth
AU - Challa, Anil K.
N1 - Funding Information:
We are grateful to the National Science Foundation for their financial support (National Science Foundation Award # 1823595) for this workshop, the Association of Biology Laboratory Educators for allowing us to connect the workshop to their Annual Meeting, the members of the Center for Life Science Education, Drs. Jared Talbot, Sharon Amacher, Amanda Simcox, and Harald Vaessin in the Department of Molecular Genetics at The Ohio State University. We also thank Dr. Misty Thomas of North Carolina A&T State University, Dr. Catherine Crosby of Clark College, and Dr. Alma Rodriguez-Estrada of Aurora University for their critical reviews of this manuscript. The authors declare that there are no conflicts of interest.
Funding Information:
We are grateful to the National Science Foundation for their financial support (National Science Foundation Award # 1823595) for this workshop, the Association of Biology Laboratory Educators for allowing us to connect the workshop to their Annual Meeting, the members of the Center for Life Science Education, Drs. Jared Talbot, Sharon Amacher, Amanda Simcox, and Harald Vaessin in the Department of Molecular Genetics at The Ohio State
Funding Information:
To help facilitate easy transfer of CRISPR-Cas9 technology into undergraduate classrooms, a two-anda-half-day workshop sponsored by the National Science Foundation (Award # 1823595) was held immediately preceding the 2018 Association of Biology Educators (ABLE) Annual Meeting at The Ohio State University. Educators from the spectrum of undergraduate institutions participated in the workshop, including those from two-year colleges, liberal arts institutions, and research universities. Although only 25% of participants had prior experience with CRISPR-Cas9, everyone was prepared to incorporate CRISPR-Cas9 into their undergraduate courses by the end of the workshop. This report summarizes the work done at this workshop, including experimentation with a workflow that can be employed at a variety of institutions and adapted for use in a variety of model organisms as well as ways in which participants could overcome hurdles in CRISPR-Cas9 implementation.
PY - 2019
Y1 - 2019
N2 - As CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 technology becomes more mainstream in life science research, it becomes critical for undergraduate instructors to devise engaging ways to bring the technology into their classrooms. To help meet this challenge, the National Science Foundation sponsored a workshop for undergraduate instructors in June 2018 at The Ohio State University in conjunction with the annual Association of Biology Laboratory Educators meeting based on a workflow developed by the workshop's facilitators. Over the course of two and a half days, participants worked through a modular workflow for the use of CRISPR-Cas9 in a course-based (undergraduate) research experience (CURE) setting while discussing the barriers each of their institutions had to implementing such work, and how such barriers could be overcome. The result of the workshop was a team with newfound energy and confidence to implement CRISPR-Cas9 technology in their courses and the development of a community of undergraduate educators dedicated to supporting each other in the implementation of the workflow either in a CURE or modular format. In this article, we review the activities and discussions from the workshop that helped each participant devise their own tailored approaches of how best to bring this exciting new technology into their classes.
AB - As CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 technology becomes more mainstream in life science research, it becomes critical for undergraduate instructors to devise engaging ways to bring the technology into their classrooms. To help meet this challenge, the National Science Foundation sponsored a workshop for undergraduate instructors in June 2018 at The Ohio State University in conjunction with the annual Association of Biology Laboratory Educators meeting based on a workflow developed by the workshop's facilitators. Over the course of two and a half days, participants worked through a modular workflow for the use of CRISPR-Cas9 in a course-based (undergraduate) research experience (CURE) setting while discussing the barriers each of their institutions had to implementing such work, and how such barriers could be overcome. The result of the workshop was a team with newfound energy and confidence to implement CRISPR-Cas9 technology in their courses and the development of a community of undergraduate educators dedicated to supporting each other in the implementation of the workflow either in a CURE or modular format. In this article, we review the activities and discussions from the workshop that helped each participant devise their own tailored approaches of how best to bring this exciting new technology into their classes.
UR - http://www.scopus.com/inward/record.url?scp=85070746657&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070746657&partnerID=8YFLogxK
U2 - 10.1128/jmbe.v20i1.1702
DO - 10.1128/jmbe.v20i1.1702
M3 - Review article
AN - SCOPUS:85070746657
VL - 20
JO - Journal of Microbiology and Biology Education
JF - Journal of Microbiology and Biology Education
SN - 1935-7877
IS - 1
ER -