Inhibitory effects of 6-O-acylated L-ascorbic acids possessing a straight- or branched-acyl chain on Epstein-Barr virus activation

Shinichi Uesato, Yutaka Kitagawa, Tomohiro Kaijima, Harukuni Tokuda, Masao Okuda, Xiao Yang Mou, Teruo Mukainaka, Hoyoku Nishino

Research output: Contribution to journalArticle

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Abstract

6-O-Acylated L-ascorbic acids possessing a straight- or branched-acyl chain of varying length from C4 to C18 have been synthesized and evaluated their anti-tumor promoting effects on the activation of the Epstein-Barr virus early antigen. The derivatives having a straight- or branched-acyl chain of C6 to C11 carbon atoms exhibited marked effects.

Original languageEnglish (US)
Pages (from-to)143-146
Number of pages4
JournalCancer Letters
Volume166
Issue number2
DOIs
StatePublished - May 26 2001

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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    Uesato, S., Kitagawa, Y., Kaijima, T., Tokuda, H., Okuda, M., Mou, X. Y., Mukainaka, T., & Nishino, H. (2001). Inhibitory effects of 6-O-acylated L-ascorbic acids possessing a straight- or branched-acyl chain on Epstein-Barr virus activation. Cancer Letters, 166(2), 143-146. https://doi.org/10.1016/S0304-3835(01)00444-X