Abstract
The gram-negative bacterial pathogen Pseudomonas aeruginosa represents a prominent clinical concern. Due to the observed high levels of antibiotic resistance, copious biofilm formation, and wide array of virulence factors produced by these bacteria, new treatment technologies are required. Here, we present the development of a series of P. aeruginosa LecA-targeted polymeric nanoparticles and demonstrate the anti-adhesion and biofilm inhibitory properties of these constructs.
Original language | English (US) |
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Article number | 55 |
Journal | Pathogens |
Volume | 8 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2019 |
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Molecular Biology
- General Immunology and Microbiology
- Microbiology (medical)
- Infectious Diseases