Human platelet and fluorochemical interaction

James J. Kmetzo, T. Peter Stein, Herbert W. Wallace

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Since the fluorochemicals have become of interest for the development of artificial red blood cells, oxygenators, liquid breathing, and as a radiographic contrast medium, their interaction with biological substances is of importance. Fresh human platelets were placed in contact with four different fluorochemicals for a period of 50 min. The platelet function as measured by aggregation was determined before and after fluorochemical contact. Appropriate controls were also evaluated. No significant differences were found between the aggregation of platelets contacted with fluorochemicals and the aggregation of platelets from the same donor unexposed to fluorochemicals.

Original languageEnglish (US)
Pages (from-to)847-858
Number of pages12
JournalJournal of Biomedical Materials Research
Issue number6
StatePublished - Nov 1977
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering


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