From Binswanger's disease to leuokoaraiosis: What we have learned about subcortical vascular dementia

David J. Libon, Catherine C. Price, Kelly Davis Garrett, Tania Giovannetti

Research output: Contribution to journalReview articlepeer-review

42 Scopus citations

Abstract

The literature regarding subcortical vascular dementia associated with periventricular and deep white matter alterations is reviewed. Information pertaining to neuropathological, neuropsychological, and neuroradiological studies is emphasized. Based on this review and prior neuropsychological studies associating subcortical vascular pathology with greater deficits on tests of executive dysfunction and with relatively better performance on tests of delayed recognition memory, we conclude that vascular dementia associated with periventricular and deep white matter alterations can and should be regarded as a subcortical dementing illness. Also, we support schemes suggested by Erkinjuntti et al. (2000) and Cosentino et al. (this issue) that attempt to integrate neuropsychological and neuroradiological data into a diagnostic paradigm that describes, as well as diagnoses, dementing disorders. We discuss questions and issues about vascular dementia that deserve further consideration and study.

Original languageEnglish (US)
Pages (from-to)83-100
Number of pages18
JournalClinical Neuropsychologist
Volume18
Issue number1
DOIs
StatePublished - Feb 2004
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Clinical Psychology
  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health

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