First total synthesis of pro-resolving and tissue-regenerative Maresin sulfido-conjugates

Keyphrases

• First Total Synthesis 100%
• Maresins 100%
• Pro-resolving 100%
• Methyl Ester 66%
• Glutathione 33%
• Epoxy 33%
• Cysteine 33%
• Epoxides 33%
• Total Synthesis 33%
• Epoxide Ring Opening 33%
• Stereospecific 33%
• Docosahexaenoic Acid 33%
• Chiral Pool 33%
• Wittig Reaction 33%
• Pooling Strategy 33%
• Hydrochloride 33%
• MCTR1 33%
• Cysteinylglycine 33%
• 2-deoxy-D-ribose (2dDR) 33%

Chemistry

• Epoxide 100%
• Methyl Ester 100%
• Pool 50%
• Cysteine 50%
• Ribose 50%
• Wittig Reaction 50%
• Docosahexaenoic Acid 50%
• Glutathione 50%