Abstract
Despite the extensive literature on drug-related behaviors and theories of reward and reinforcement, the physiological bases of many other aspects of the actions of abusepotential substances, drug dependence, and development of chronic patterns of substance abuse are not well understood. These include drug craving, tolerance, sensitization, and withdrawal. A better delineation of the physiological mechanisms influenced by recreational drugs and the neural network functions that are biased by acute and chronic patterns of substance abuse may lead to more rational and effective therapies for drug addiction.
Original language | English (US) |
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Title of host publication | Methods in Drug Abuse Research |
Subtitle of host publication | Cellular and Circuit Level Analyses |
Publisher | CRC Press |
Pages | 111-142 |
Number of pages | 32 |
ISBN (Electronic) | 9781420038682 |
ISBN (Print) | 0849323452, 9780849323454 |
State | Published - Jan 1 2002 |
All Science Journal Classification (ASJC) codes
- Neuroscience(all)
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)