TY - JOUR
T1 - Efficacy of platelet-rich plasma for sacroiliac joint dysfunction
T2 - a qualitative systematic review with pooled analysis
AU - Goodwin, Brandon
AU - Averell, Nicholas
AU - Al-Shehab, Usmaan
AU - Ernazarov, Akhmad
AU - Price, Lisa
AU - Choudhary, Akhil
AU - Jermyn, Richard
N1 - Publisher Copyright:
© 2023 Future Medicine Ltd.
PY - 2023/6/1
Y1 - 2023/6/1
N2 - Aim: We aimed to expound upon previous research examining the effect of platelet rich plasma in the treatment of sacroiliac joint (SIJ) dysfunction and pain. Materials & methods: A systematic review was employed in conjunction with a pooled analysis of the efficacy of platelet-rich plasma (PRP) in SIJ dysfunction and pain. Results: A total of 259 articles were retrieved following database systematic review. As a result, four clinical trials and two case studies were subjected to full text appraisal. The dates of publication ranged from 2015 to 2022. Conclusion: Although a unique modality, there is not enough evidence to support the employment of PRP injections over current steroid standard of care. Further double-blinded, randomized control trials are required to elucidate PRP role in SIJ dysfunction. Plain language summary Platelet rich plasma is an injection derived from separating blood components in a centrifuge. Injection of platelet rich plasma into the sacroiliac joint has often been touted as highly beneficial for pain and disability, and superior to other modalities. Our systematic review and pooled analysis show that platelet rich plasma injections are beneficial, albeit not to the degree previously reported.
AB - Aim: We aimed to expound upon previous research examining the effect of platelet rich plasma in the treatment of sacroiliac joint (SIJ) dysfunction and pain. Materials & methods: A systematic review was employed in conjunction with a pooled analysis of the efficacy of platelet-rich plasma (PRP) in SIJ dysfunction and pain. Results: A total of 259 articles were retrieved following database systematic review. As a result, four clinical trials and two case studies were subjected to full text appraisal. The dates of publication ranged from 2015 to 2022. Conclusion: Although a unique modality, there is not enough evidence to support the employment of PRP injections over current steroid standard of care. Further double-blinded, randomized control trials are required to elucidate PRP role in SIJ dysfunction. Plain language summary Platelet rich plasma is an injection derived from separating blood components in a centrifuge. Injection of platelet rich plasma into the sacroiliac joint has often been touted as highly beneficial for pain and disability, and superior to other modalities. Our systematic review and pooled analysis show that platelet rich plasma injections are beneficial, albeit not to the degree previously reported.
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U2 - 10.2217/rme-2022-0211
DO - 10.2217/rme-2022-0211
M3 - Review article
C2 - 37199253
AN - SCOPUS:85163920602
SN - 1746-0751
VL - 18
SP - 505
EP - 514
JO - Regenerative Medicine
JF - Regenerative Medicine
IS - 6
ER -