Effects of dehydration on the viscoelastic properties of vocal folds in large deformations

Amir K. Miri, François Barthelat, Luc Mongeau

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Dehydration may alter vocal fold viscoelastic properties, thereby hampering phonation. The effects of water loss induced by an osmotic pressure potential on vocal fold tissue viscoelastic properties were investigated. Porcine vocal folds were dehydrated by immersion in a hypertonic solution, and quasi-static and low-frequency dynamic traction tests were performed for elongations of up to 50%. Digital image correlation was used to determine local strains from surface deformations. The elastic modulus and the loss factor were then determined for normal and dehydrated tissues. An eight-chain hyperelastic model was used to describe the observed nonlinear stress-stretch behavior. Contrary to the expectations, the mass history indicated that the tissue absorbed water during cyclic extension when submerged in a hypertonic solution. During loading history, the elastic modulus was increased for dehydrated tissues as a function of strain. The response of dehydrated tissues was much less affected when the load was released. This observation suggests that hydration should be considered in micromechanical models of the vocal folds. The internal hysteresis, which is often linked to phonation effort, increased significantly with water loss. The effects of dehydration on the viscoelastic properties of vocal fold tissue were quantified in a systematic way. A better understanding of the role of hydration on the mechanical properties of vocal fold tissue may help to establish objective dehydration and phonotrauma criteria.

Original languageEnglish (US)
Pages (from-to)688-697
Number of pages10
JournalJournal of Voice
Volume26
Issue number6
DOIs
StatePublished - Nov 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Speech and Hearing
  • LPN and LVN

Fingerprint

Dive into the research topics of 'Effects of dehydration on the viscoelastic properties of vocal folds in large deformations'. Together they form a unique fingerprint.

Cite this