Effect of essential fatty acid deficiency on myocardial ischemia

C. E. Hock, J. A. Michalski, D. K. Reibel, A. M. Lefer

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Acute myocardial ischemia was studied in Sprague-Dawley rats fed a normal diet and in rats fed an essential fatty acid deficient (EFAD) diet for 11 weeks. EFAD diet rats had a significantly lower body weight than control rats, and exhibited a striking difference in left ventricular phospholipid content characterized by a large increase in palmitoleic and oleic acids and a marked decrease in linoleic acid. Despite these differences, EFAD diet rats subjected to acute myocardial ischemia showed no difference in the severity of ischemic damage to the myocardium as assessed by myocardial creatine kinase activity.

Original languageEnglish (US)
Pages (from-to)404-405
Number of pages2
JournalIRCS Medical Science
Volume13
Issue number5
StatePublished - 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology

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