Differential lexical and semantic spreading activation in Alzheimer's disease

Paul S. Foster; Valeria Drago; Raegan C. Yung; Jaclyn Pearson; Kristi Stringer; Tania Giovannetti; David Libon; Kenneth M. Heilman

doi:10.1177/1533317513494445

Differential lexical and semantic spreading activation in Alzheimer's disease

Paul S. Foster, Valeria Drago, Raegan C. Yung, Jaclyn Pearson, Kristi Stringer, Tania Giovannetti, David Libon, Kenneth M. Heilman

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Alzheimer's disease (AD) is known to be associated with disruption in semantic networks. Previous studies examining changes in spreading activation in AD have used a lexical decision task paradigm. We have used a paradigm based on average word frequencies obtained from the words generated on the Controlled Oral Word Association Test (COWAT) and the Animal Naming (AN) test. The COWAT and AN tests were administered to a group of 25 patients with AD and 20 control participants. We predicted that the patients with AD would have higher average word frequencies on the COWAT and AN tests than the control participants. The results indicated that the AD group generated words with a higher average word frequency on the AN test but a lower average word frequency on the COWAT. The reasons for the discrepancy in average word frequencies on the AN test and COWAT are discussed.

Original language	English (US)
Pages (from-to)	501-507
Number of pages	7
Journal	American Journal of Alzheimer's Disease and other Dementias
Volume	28
Issue number	5
DOIs	https://doi.org/10.1177/1533317513494445
State	Published - Aug 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Neuroscience
Clinical Psychology
Geriatrics and Gerontology
Psychiatry and Mental health

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Cite this

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title = "Differential lexical and semantic spreading activation in Alzheimer's disease",

abstract = "Alzheimer's disease (AD) is known to be associated with disruption in semantic networks. Previous studies examining changes in spreading activation in AD have used a lexical decision task paradigm. We have used a paradigm based on average word frequencies obtained from the words generated on the Controlled Oral Word Association Test (COWAT) and the Animal Naming (AN) test. The COWAT and AN tests were administered to a group of 25 patients with AD and 20 control participants. We predicted that the patients with AD would have higher average word frequencies on the COWAT and AN tests than the control participants. The results indicated that the AD group generated words with a higher average word frequency on the AN test but a lower average word frequency on the COWAT. The reasons for the discrepancy in average word frequencies on the AN test and COWAT are discussed.",

author = "Foster, \{Paul S.\} and Valeria Drago and Yung, \{Raegan C.\} and Jaclyn Pearson and Kristi Stringer and Tania Giovannetti and David Libon and Heilman, \{Kenneth M.\}",

year = "2013",

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T1 - Differential lexical and semantic spreading activation in Alzheimer's disease

AU - Foster, Paul S.

AU - Drago, Valeria

AU - Yung, Raegan C.

AU - Pearson, Jaclyn

AU - Stringer, Kristi

AU - Giovannetti, Tania

AU - Libon, David

AU - Heilman, Kenneth M.

PY - 2013/8

Y1 - 2013/8

N2 - Alzheimer's disease (AD) is known to be associated with disruption in semantic networks. Previous studies examining changes in spreading activation in AD have used a lexical decision task paradigm. We have used a paradigm based on average word frequencies obtained from the words generated on the Controlled Oral Word Association Test (COWAT) and the Animal Naming (AN) test. The COWAT and AN tests were administered to a group of 25 patients with AD and 20 control participants. We predicted that the patients with AD would have higher average word frequencies on the COWAT and AN tests than the control participants. The results indicated that the AD group generated words with a higher average word frequency on the AN test but a lower average word frequency on the COWAT. The reasons for the discrepancy in average word frequencies on the AN test and COWAT are discussed.

AB - Alzheimer's disease (AD) is known to be associated with disruption in semantic networks. Previous studies examining changes in spreading activation in AD have used a lexical decision task paradigm. We have used a paradigm based on average word frequencies obtained from the words generated on the Controlled Oral Word Association Test (COWAT) and the Animal Naming (AN) test. The COWAT and AN tests were administered to a group of 25 patients with AD and 20 control participants. We predicted that the patients with AD would have higher average word frequencies on the COWAT and AN tests than the control participants. The results indicated that the AD group generated words with a higher average word frequency on the AN test but a lower average word frequency on the COWAT. The reasons for the discrepancy in average word frequencies on the AN test and COWAT are discussed.

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Differential lexical and semantic spreading activation in Alzheimer's disease

Abstract

All Science Journal Classification (ASJC) codes

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