1. 1. Diazepam (Valium/Roche) inhibited the morphogenesis of explanted stage 8 chick embryos in a dose-related manner. 2. 2. Diazepam, at concn of 400-500 Mg/ml, preferentially inhibited closure of the neural tube. This inhibition was accompanied by a significant reduction in myosin content of the developing neuroepithelium. 3. 3. Diazepam can be used as a probe to study the contributory role of myosin in cellular and morphogenetic movements.
|Original language||English (US)|
|Number of pages||4|
|Journal||Comparative Biochemistry and Physiology. Part C, Comparative|
|State||Published - 1984|
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