Diastereoselective synthesis of substituted diaziridines from simple ketones and aldehydes

Alexander W. Beebe, Emma F. Dohmeier, Gustavo Moura-Letts

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Diastereopure substituted diaziridines from simple ketones, aldehydes and amines are here reported. These important chemical scaffolds are obtained in the presence of a weak inorganic base and hydroxylamine O-sulfonic acid (HOSA). This method introduces three stereocenters in one step to provide a wide variety of substituted diaziridines with high yields and diastereoselectivities.

Original languageEnglish (US)
Pages (from-to)13511-13514
Number of pages4
JournalChemical Communications
Volume51
Issue number70
DOIs
StatePublished - Jul 20 2015

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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