TY - JOUR
T1 - Development of an integrated network visualisation and graph analysis tool for biological networks
AU - Tang, Ying
AU - Carbonetta, David
AU - Shetty, Sachin
PY - 2012/7
Y1 - 2012/7
N2 - There has been a steady increase in the amount of molecular data generated by experiments and computational methods performed on biological networks. There is a growing need to obtain an insight into the organisation and structure of the massive and complex biological networks formed by the interacting molecules. To that end, this paper presents a newly developed plugin for integrated network visualisation and graph analysis within the Cytoscape framework. The plugin is capable of computing and visualising a comprehensive set of node and graph level statistics. The evaluation of the plugin on a range of biological networks and its memory performance is conducted. The plugin, proven to be scalable, is an interactive and highly customisable application that expects no prior knowledge in graph theory from users.
AB - There has been a steady increase in the amount of molecular data generated by experiments and computational methods performed on biological networks. There is a growing need to obtain an insight into the organisation and structure of the massive and complex biological networks formed by the interacting molecules. To that end, this paper presents a newly developed plugin for integrated network visualisation and graph analysis within the Cytoscape framework. The plugin is capable of computing and visualising a comprehensive set of node and graph level statistics. The evaluation of the plugin on a range of biological networks and its memory performance is conducted. The plugin, proven to be scalable, is an interactive and highly customisable application that expects no prior knowledge in graph theory from users.
UR - http://www.scopus.com/inward/record.url?scp=84864718585&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864718585&partnerID=8YFLogxK
U2 - 10.1504/IJCBDD.2012.048318
DO - 10.1504/IJCBDD.2012.048318
M3 - Article
C2 - 22854123
AN - SCOPUS:84864718585
SN - 1756-0756
VL - 5
SP - 152
EP - 163
JO - International Journal of Computational Biology and Drug Design
JF - International Journal of Computational Biology and Drug Design
IS - 2
ER -