CSF γ-aminobutyric acid in alcoholics and control subjects

Alec Roy, Judith Dejong, Thomas Ferraro, Bryon Adinoff, Bernard Ravitz, Markku Linnoila

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Alcohol has widespread effects on the γ-aminobutyric acid (GABA) system in the brain. This system in the brain is also postulated to have a role in anxiety, and alcoholics have been reported to have more anxiety disorders. Therefore, the authors undertook a study to compare CSF levels of GABA in abstinent alcoholic patients and normal control subjects. There was no significant difference between groups in CSF levels of GABA. Also, there was no significant difference in GABA level between alcoholic patients with histories of withdrawal seizures and those without such a history.

Original languageEnglish (US)
Pages (from-to)1294-1296
Number of pages3
JournalAmerican Journal of Psychiatry
Issue number10
StatePublished - Jan 1 1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health


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