Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

Sadaaki Tamura; Narihiko Fukamiya; Xiao Yang Mou; Teruo Mukainaka; Harukuni Tokuda; Hoyoku Nishino; Kiyoshi Tagahara; Kazuo Koike; Kuo Hsiung Lee; Masayoshi Okano

doi:10.1248/cpb.48.876

Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

Sadaaki Tamura, Narihiko Fukamiya, Xiao Yang Mou, Teruo Mukainaka, Harukuni Tokuda, Hoyoku Nishino, Kiyoshi Tagahara, Kazuo Koike, Kuo Hsiung Lee, Masayoshi Okano

Chemistry

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.

Original language	English (US)
Pages (from-to)	876-878
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	48
Issue number	6
DOIs	https://doi.org/10.1248/cpb.48.876
State	Published - Jun 2000

All Science Journal Classification (ASJC) codes

Chemistry(all)
Drug Discovery

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10.1248/cpb.48.876

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Tamura, S., Fukamiya, N., Mou, X. Y., Mukainaka, T., Tokuda, H., Nishino, H., Tagahara, K., Koike, K., Lee, K. H., & Okano, M. (2000). Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol. Chemical and Pharmaceutical Bulletin, 48(6), 876-878. https://doi.org/10.1248/cpb.48.876

Tamura, Sadaaki ; Fukamiya, Narihiko ; Mou, Xiao Yang ; Mukainaka, Teruo ; Tokuda, Harukuni ; Nishino, Hoyoku ; Tagahara, Kiyoshi ; Koike, Kazuo ; Lee, Kuo Hsiung ; Okano, Masayoshi. / Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol. In: Chemical and Pharmaceutical Bulletin. 2000 ; Vol. 48, No. 6. pp. 876-878.

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title = "Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol",

abstract = "Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.",

author = "Sadaaki Tamura and Narihiko Fukamiya and Mou, {Xiao Yang} and Teruo Mukainaka and Harukuni Tokuda and Hoyoku Nishino and Kiyoshi Tagahara and Kazuo Koike and Lee, {Kuo Hsiung} and Masayoshi Okano",

year = "2000",

month = jun,

doi = "10.1248/cpb.48.876",

language = "English (US)",

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pages = "876--878",

journal = "Chemical and Pharmaceutical Bulletin",

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Tamura, S, Fukamiya, N, Mou, XY, Mukainaka, T, Tokuda, H, Nishino, H, Tagahara, K, Koike, K, Lee, KH & Okano, M 2000, 'Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol', Chemical and Pharmaceutical Bulletin, vol. 48, no. 6, pp. 876-878. https://doi.org/10.1248/cpb.48.876

Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol. / Tamura, Sadaaki; Fukamiya, Narihiko; Mou, Xiao Yang; Mukainaka, Teruo; Tokuda, Harukuni; Nishino, Hoyoku; Tagahara, Kiyoshi; Koike, Kazuo; Lee, Kuo Hsiung; Okano, Masayoshi.

In: Chemical and Pharmaceutical Bulletin, Vol. 48, No. 6, 06.2000, p. 876-878.

Research output: Contribution to journal › Article › peer-review

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T1 - Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

AU - Tamura, Sadaaki

AU - Fukamiya, Narihiko

AU - Mou, Xiao Yang

AU - Mukainaka, Teruo

AU - Tokuda, Harukuni

AU - Nishino, Hoyoku

AU - Tagahara, Kiyoshi

AU - Koike, Kazuo

AU - Lee, Kuo Hsiung

AU - Okano, Masayoshi

PY - 2000/6

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N2 - Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.

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