Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

Sadaaki Tamura; Narihiko Fukamiya; Xiao Yang Mou; Teruo Mukainaka; Harukuni Tokuda; Hoyoku Nishino; Kiyoshi Tagahara; Kazuo Koike; Kuo Hsiung Lee; Masayoshi Okano

doi:10.1248/cpb.48.876

Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

Sadaaki Tamura, Narihiko Fukamiya, Xiao Yang Mou, Teruo Mukainaka, Harukuni Tokuda, Hoyoku Nishino, Kiyoshi Tagahara, Kazuo Koike, Kuo Hsiung Lee, Masayoshi Okano

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.

Original language	English (US)
Pages (from-to)	876-878
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	48
Issue number	6
DOIs	https://doi.org/10.1248/cpb.48.876
State	Published - Jun 2000
Externally published	Yes

All Science Journal Classification (ASJC) codes

Chemistry(all)
Drug Discovery

Access to Document

10.1248/cpb.48.876

Cite this

Tamura, S., Fukamiya, N., Mou, X. Y., Mukainaka, T., Tokuda, H., Nishino, H., Tagahara, K., Koike, K., Lee, K. H., & Okano, M. (2000). Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol. Chemical and Pharmaceutical Bulletin, 48(6), 876-878. https://doi.org/10.1248/cpb.48.876

@article{aa4ade0cbaa74fe6adb5d1c901bec685,

title = "Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol",

abstract = "Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.",

author = "Sadaaki Tamura and Narihiko Fukamiya and Mou, {Xiao Yang} and Teruo Mukainaka and Harukuni Tokuda and Hoyoku Nishino and Kiyoshi Tagahara and Kazuo Koike and Lee, {Kuo Hsiung} and Masayoshi Okano",

year = "2000",

month = jun,

doi = "10.1248/cpb.48.876",

language = "English (US)",

volume = "48",

pages = "876--878",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "6",

}

Tamura, S, Fukamiya, N, Mou, XY, Mukainaka, T, Tokuda, H, Nishino, H, Tagahara, K, Koike, K, Lee, KH & Okano, M 2000, 'Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol', Chemical and Pharmaceutical Bulletin, vol. 48, no. 6, pp. 876-878. https://doi.org/10.1248/cpb.48.876

Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol. / Tamura, Sadaaki; Fukamiya, Narihiko; Mou, Xiao Yang et al.

In: Chemical and Pharmaceutical Bulletin, Vol. 48, No. 6, 06.2000, p. 876-878.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

AU - Tamura, Sadaaki

AU - Fukamiya, Narihiko

AU - Mou, Xiao Yang

AU - Mukainaka, Teruo

AU - Tokuda, Harukuni

AU - Nishino, Hoyoku

AU - Tagahara, Kiyoshi

AU - Koike, Kazuo

AU - Lee, Kuo Hsiung

AU - Okano, Masayoshi

PY - 2000/6

Y1 - 2000/6

N2 - Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.

AB - Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.

UR - http://www.scopus.com/inward/record.url?scp=0033949339&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033949339&partnerID=8YFLogxK

U2 - 10.1248/cpb.48.876

DO - 10.1248/cpb.48.876

M3 - Article

C2 - 10866153

AN - SCOPUS:0033949339

SN - 0009-2363

VL - 48

SP - 876

EP - 878

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 6

ER -

Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this