Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol

Sadaaki Tamura, Narihiko Fukamiya, Xiao Yang Mou, Teruo Mukainaka, Harukuni Tokuda, Hoyoku Nishino, Kiyoshi Tagahara, Kazuo Koike, Kuo Hsiung Lee, Masayoshi Okano

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.

Original languageEnglish (US)
Pages (from-to)876-878
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume48
Issue number6
DOIs
StatePublished - Jun 2000

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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