Controlled architecture for improved macromolecular memory within polymer networks

Stephen A. DiPasquale, Mark E. Byrne

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

This brief review analyzes recent developments in the field of living/controlled polymerization and the potential of this technique for creating imprinted polymers with highly structured architecture with macromolecular memory. As a result, it is possible to engineer polymers at the molecular level with increased homogeneity relating to enhanced template binding and transport. Only recently has living/controlled polymerization been exploited to decrease heterogeneity and substantially improve the efficiency of the imprinting process for both highly and weakly crosslinked imprinted polymers. Living polymerization can be utilized to create imprinted networks that are vastly more efficient than similar polymers produced using conventional free radical polymerization, and these improvements increase the role that macromolecular memory can play in the design and engineering of new drug delivery and sensing platforms.

Original languageEnglish (US)
Pages (from-to)170-176
Number of pages7
JournalCurrent Opinion in Biotechnology
Volume40
DOIs
StatePublished - Aug 1 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Fingerprint

Dive into the research topics of 'Controlled architecture for improved macromolecular memory within polymer networks'. Together they form a unique fingerprint.

Cite this