TY - JOUR
T1 - Cerebrovascular disease and cognition in older adults
AU - Seidel, Gregory A.
AU - Giovannetti, Tania
AU - Libon, David J.
PY - 2011/7/20
Y1 - 2011/7/20
N2 - The well-established association between advanced age, cerebrovascular pathology, and cognitive decline is receiving greater attention as the population attains new levels of longevity. This chapter will provide an overview of vascular anatomy and age-related cerebrovascular disorders and diseases, including stroke and degenerative dementia. The cognitive and functional sequellae of these cerebrovascular disorders will also be described in detail. Throughout this review, we will emphasize topics that have been relatively underrepresented in the literature, including age-related diseases of the cerebral small vessels, nuanced characterization of cognitive impairment associated with insidious small-vessel vascular dementia, and the real-life functional consequences of cerebrovascular changes in older adults.
AB - The well-established association between advanced age, cerebrovascular pathology, and cognitive decline is receiving greater attention as the population attains new levels of longevity. This chapter will provide an overview of vascular anatomy and age-related cerebrovascular disorders and diseases, including stroke and degenerative dementia. The cognitive and functional sequellae of these cerebrovascular disorders will also be described in detail. Throughout this review, we will emphasize topics that have been relatively underrepresented in the literature, including age-related diseases of the cerebral small vessels, nuanced characterization of cognitive impairment associated with insidious small-vessel vascular dementia, and the real-life functional consequences of cerebrovascular changes in older adults.
UR - http://www.scopus.com/inward/record.url?scp=84886722313&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84886722313&partnerID=8YFLogxK
U2 - 10.1007/7854_2011_140
DO - 10.1007/7854_2011_140
M3 - Article
C2 - 21773915
AN - SCOPUS:84886722313
VL - 10
SP - 213
EP - 241
JO - Current Topics in Behavioral Neurosciences
JF - Current Topics in Behavioral Neurosciences
SN - 1866-3370
ER -