Brain glycosaminoglycans (Mucopolysaccharides) following intrauterine growth retardation

N. S. Vasan, H. P. Chase

Research output: Contribution to journalArticlepeer-review


The concentration of total brain glycosaminoglycan (mucopolysaccharide) was reduced 33% in three small for gestational age (SGA) infants compared to 3 control infants. The three major fractions, hyaluronic acid, chondroitin sulfate, and heparan sulfate were reduced by 55, 32, and 36%, respectively, in the SGA brains. The percent hyaluronidase resistant material and the major type of hexosamine were similar in the fractions from SGA and control brains. Total hexosamine was reduced by 50% in the hyaluronic acid and heparan sulfate fractions, and increased by 35% in a third fraction of the SGA brains.

Original languageEnglish (US)
Pages (from-to)196-206
Number of pages11
Issue number3-4
StatePublished - 1976
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Developmental Biology


Dive into the research topics of 'Brain glycosaminoglycans (Mucopolysaccharides) following intrauterine growth retardation'. Together they form a unique fingerprint.

Cite this