Abstract
The concentration of total brain glycosaminoglycan (mucopolysaccharide) was reduced 33% in three small for gestational age (SGA) infants compared to 3 control infants. The three major fractions, hyaluronic acid, chondroitin sulfate, and heparan sulfate were reduced by 55, 32, and 36%, respectively, in the SGA brains. The percent hyaluronidase resistant material and the major type of hexosamine were similar in the fractions from SGA and control brains. Total hexosamine was reduced by 50% in the hyaluronic acid and heparan sulfate fractions, and increased by 35% in a third fraction of the SGA brains.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 196-206 |
| Number of pages | 11 |
| Journal | Neonatology |
| Volume | 28 |
| Issue number | 3-4 |
| DOIs | |
| State | Published - 1976 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Developmental Biology