Biomimetic polymers in drug delivery and sensing applications: Effect of network molecular structure on recognition properties

J. Zach Hilt, Nicholas A. Peppas, Mark E. Byrne

    Research output: Contribution to conferencePaperpeer-review

    2 Scopus citations

    Abstract

    The binding and release kinetics of the biomimetic polymer networks, which are used in biosensing and controlled drug delivery, were investigated. The effect of the network molecular structure on the diffusion coefficient of D-glucose fluorescent analogue, 2-NBDG, was also investigated. The polymer networks specific for a target biomolecule were micropatterned onto silicon substrates, and characterized by single and competitive fluorescent and confocal microscopy, SEM , and profilometry. It was found that with decreasing crosslinking percentage of the network, the macromolecular recognition of the network chains decreases.

    Original languageEnglish (US)
    Pages1119-1121
    Number of pages3
    StatePublished - Dec 1 2004
    Event2004 AIChE Annual Meeting - Austin, TX, United States
    Duration: Nov 7 2004Nov 12 2004

    Other

    Other2004 AIChE Annual Meeting
    CountryUnited States
    CityAustin, TX
    Period11/7/0411/12/04

    All Science Journal Classification (ASJC) codes

    • Engineering(all)

    Fingerprint Dive into the research topics of 'Biomimetic polymers in drug delivery and sensing applications: Effect of network molecular structure on recognition properties'. Together they form a unique fingerprint.

    Cite this