Biodegradable composites with aligned hydroxyapatite nanoneedles

Shih Po Sun, Mei Wei, James R. Olson, Montgomery T. Shaw

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We prepared an anisotropic bone graft composite to mimic the hierarchical structure of the natural bone in which aligned hydroxyapatite (HA) nanocrystals deposit along collagen fibers. To approach the modulus and strength of the bone, we incorporated synthesized HA nanoneedles and melt drawn poly(L-lactic acid) fibers in our composite as reinforcing components. Their preferred orientation was induced via a modified pultrusion process. The HA orientation distribution was examined using wide angle X-ray diffraction. Micromechanical Halpin-Tsai model predictions considering the amount, shape, and orientation distribution of HA were compared, favorably, with the experimental observations. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.

Original languageEnglish (US)
Pages (from-to)1817-1825
Number of pages9
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume100 B
Issue number7
DOIs
StatePublished - Oct 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering

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