Anidulafungin: A drug evaluation of a new echinocandin

Jomy M. Joseph, Rose Kim, Annette C. Reboli

    Research output: Contribution to journalArticle

    11 Scopus citations

    Abstract

    Background: Over the past two decades, the frequency and type of invasive fungal infections have increased greatly and thus have driven the need for new antifungal agents. Anidulafungin is the newest addition to the echinocandin armamentarium. Objective: The intention of this review is to provide a drug evaluation of anidulafungin, including its spectrum of activity, pharmacokinetics, pharmacodynamics, clinical efficacy, adverse event profile, and its role in the treatment of invasive candidiasis. Methods: A PubMed search was performed to gather the most current and pertinent articles. Conclusions: Clinical trials have demonstrated anidulafungin's efficacy and tolerability in invasive candidiasis. Anidulafungin is not associated with any drug-drug interactions and does not require dosage adjustment in patients with renal and/or hepatic impairment.

    Original languageEnglish (US)
    Pages (from-to)2339-2348
    Number of pages10
    JournalExpert Opinion on Pharmacotherapy
    Volume9
    Issue number13
    DOIs
    StatePublished - Sep 1 2008

    All Science Journal Classification (ASJC) codes

    • Pharmacology
    • Pharmacology (medical)

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