An outbreak of Burkholderia cepacia, lower respiratory tract infection associated with contaminated albuterol nebulization solution

A. C. Reboli, R. Koshinski, K. Arias, K. Marks-Austin, D. Stieritz, T. L. Stull

    Research output: Contribution to journalArticle

    66 Scopus citations

    Abstract

    An outbreak of Burkholderia cepacia lower respiratory tract colonization and infection occurred in the adult intensive-care units in various geographic locations throughout our hospital. Forty-four patients became colonized or infected over an 11-month period, whereas B cepacia had been isolated from only 13 patients in the preceding 48 months. Environmental cultures revealed the source to be extrinsically contaminated albuterol nebulization solution. Polymerase chain reaction-ribotyping confirmed the genetic relatedness of the B cepacia patient isolates and the contaminated albuterol. After extensive infection control training for the respiratory therapy staff, including attention to nebulization technique, washing and drying the nebulizer cup, and good handwashing, there have not been any new cases.

    Original languageEnglish (US)
    Pages (from-to)741-743
    Number of pages3
    JournalInfection Control and Hospital Epidemiology
    Volume17
    Issue number11
    DOIs
    StatePublished - Nov 1996

    All Science Journal Classification (ASJC) codes

    • Epidemiology
    • Microbiology (medical)
    • Infectious Diseases

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