An efficient boric acid-mediated preparation of α-hydroxyamides

J. Sravan Kumar, Subash Jonnalagadda, Venkatram R. Mereddy

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

An efficient methodology for the preparation of α-hydroxyamides via boric acid-mediated addition of isonitriles onto aldehydes has been developed. The reaction of isonitriles with α-boronobenzaldehyde takes place under intramolecular catalysis conditions to provide functionalized benzoxaboroles.

Original languageEnglish (US)
Pages (from-to)779-782
Number of pages4
JournalTetrahedron Letters
Volume51
Issue number5
DOIs
StatePublished - Feb 3 2010

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Catalysis
Aldehydes
boric acid

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Sravan Kumar, J. ; Jonnalagadda, Subash ; Mereddy, Venkatram R. / An efficient boric acid-mediated preparation of α-hydroxyamides. In: Tetrahedron Letters. 2010 ; Vol. 51, No. 5. pp. 779-782.
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An efficient boric acid-mediated preparation of α-hydroxyamides. / Sravan Kumar, J.; Jonnalagadda, Subash; Mereddy, Venkatram R.

In: Tetrahedron Letters, Vol. 51, No. 5, 03.02.2010, p. 779-782.

Research output: Contribution to journalArticle

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