Hip implants are extremely common procedures that are performed to relieve pain and restore function to the hip joint. Historically, most implants would last for the duration of the patient's life, approximately 15 years after implantation; however, due to medical advancements patients are living longer and outliving the life of their implant. The most common cause for implant failure is the failure of the bond between the implant and the bone, occurring due to the translation or rotation of the implant. Once an implant has failed, a very invasive, costly, and painful revision surgery is required. There is significant advantage in the early detection of implant loosening. This paper presents a radial basis function based image processing technique to detect minute 3-D rotations of a hip implant from 2-D X-ray images. Comparing these rotations for a particular hip implant over time can alert orthopedic surgeons of trends that might lead to impending gross loosening of the implant and enable early correction.