Projects per year
Personal profile
Research interests
Research Expertise:
Pharmacology | Neuroscience | Biochemistry
I am interested in developing new medications for neuropsychiatric disorders, including Alzheimer’s disease, schizophrenia, ADHD, pain, anxiety, and a particular interest in drug addiction. My lab works closely with medicinal chemists to design and test new drug-like molecules, combining molecular and behavioral pharmacology methods to evaluate the preclinical potential of new compounds designed to target the dopamine D4 receptor, the µ opioid receptor, and the trace amine-associated receptor 1, among others.
Honors and Awards:
2017 Maharaj Ticku Memorial Travel Fellowship for New Investigators Award, Behavior, Biology and Chemistry Conf.
2015 Frances R. Lax Faculty Development Award, Rowan University
2013 Mentoring Award for Fellows, NIDA-IRP, NIH
2013 Postdoctoral Mentor Award, NIH
2012 & 2013 Fellows’ Award for Research Excellence, NIH
Member of:
American Society for Pharmacology and Experimental Therapeutics https://www.aspet.org/
Pharmacology Society (Councilor) https://www.aspet.org/MAPS/
Philadelphia Chapter of the Society for Neuroscience http://pcsfn.com/
Education/Academic qualification
Doctor of Philosophy, doctorate
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Combination drug therapy to treat pain with minimal or no abuse potential and side-effects
Keck, T. (PI)
National Institutes of Health (NIH)
9/30/23 → 7/31/28
Project: Other project
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Negative allosteric modulators of the D3 dopamine receptor as therapeutic leads for substance use disorders
Keck, T. (PI)
The University of North Carolina at Chapel Hill
6/1/22 → 5/31/24
Project: Other project
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Analgesia without Addiction: Synthesis and Development of 2nd Generation Novel Analgesics
Keck, T. (PI)
Foundation for Health Advancement
3/2/22 → 2/28/23
Project: Other project
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Low-Efficacy Dopamine D4 Receptor Partial Agonists for Cocaine Addiction
Keck, T. (PI)
9/30/20 → 8/31/23
Project: Other project
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Rowan University Application for 2019 Jean Dreyfus Lectureship for Undergraduate Institutions
Keck, T. (PI)
The Camille & Henry Dreyfus Foundation, Inc.
9/1/19 → 8/31/20
Project: Other project
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The CB1 negative allosteric modulator PSNCBAM-1 reduces ethanol self-administration via a nonspecific hypophagic effect
Buechler, H. M., Sumi, M., Madhuranthakam, I. M., Donegan, C., DiGiorgio, F., Acosta, A. A., Uribe, S., Rahman, M. A., Sorbello, A., Fischer, B. D. & Keck, T. M., Jul 2024, In: Pharmacology Biochemistry and Behavior. 240, 173776.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder
Boateng, C. A., Nilson, A. N., Placide, R., Pham, M. L., Jakobs, F. M., Boldizsar, N., McIntosh, S., Stallings, L. S., Korankyi, I. V., Kelshikar, S., Shah, N., Panasis, D., Muccilli, A., Ladik, M., Maslonka, B., McBride, C., Sanchez, M. X., Akca, E., Alkhatib, M. & Saez, J. & 15 others, , Sep 14 2023, In: Journal of Medicinal Chemistry. 66, 17, p. 12141-12162 22 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Decoding brain memory formation by single-cell RNA sequencing
Sardoo, A. M., Zhang, S., Ferraro, T. N., Keck, T. M. & Chen, Y., Nov 1 2022, In: Briefings in bioinformatics. 23, 6, bbac412.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants
Ferré, S., Belcher, A. M., Bonaventura, J., Quiroz, C., Sánchez-Soto, M., Casadó-Anguera, V., Cai, N. S., Moreno, E., Boateng, C. A., Keck, T. M., Florán, B., Earley, C. J., Ciruela, F., Casadó, V., Rubinstein, M. & Volkow, N. D., Sep 30 2022, In: Frontiers in Endocrinology. 13, 1014678.Research output: Contribution to journal › Review article › peer-review
Open Access22 Scopus citations -
Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D3Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders
Bonifazi, A., Newman, A. H., Keck, T. M., Gervasoni, S., Vistoli, G., Del Bello, F., Giorgioni, G., Pavletić, P., Quaglia, W. & Piergentili, A., Oct 6 2021, In: ACS chemical neuroscience. 12, 19, p. 3638-3649 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations