Projects per year
Personal profile
Research interests
Research Expertise:
Organic & Medicinal Chemistry | Organoboron Chemistry | Alternate Energy Materials
Medicinal Chemistry: We have been developing novel aza- and bora-heterocyclic compounds and betulin-based natural product derivatives as anti-cancer agents. In collaboration with Rowan School of Osteopathic Medicine, we have also identified few Withaferin-serotonin conjugates as potential therapeutic options for the treatment of Alzheimers’ Disease.
Value Added Chemicals from Biomass: Recent efforts in this area have included the development of new protocols for the effective conversion of biomass derived cellulosic materials into chemicals such as hydroxymethyl furfural and furan dicarboxylic acid for applications as bio-based polymers.
Honors and Awards:
Rowan University Wall of Fame Teaching Award, 2013, 2016
Eli Lilly International Graduate Scholar, 2000-2005, Purdue University
Member of:
American Chemical Society (www.acs.org)
Education/Academic qualification
Doctor of Philosophy, doctorate
Bachelor of Science, Bachelor, Pondicherry University
Master of Science, Master, University of Hyderabad
Fingerprint Dive into the research topics where Subash Jonnalagadda is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Pyrrolidonecarboxylic Acid
Chemical Compounds
Alkylation
Chemical Compounds
Cytotoxicity
Chemical Compounds
Boron
Chemical Compounds
Cells
Chemical Compounds
Lactams
Chemical Compounds
Derivatives
Chemical Compounds
Aldehydes
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2010 2020
Development of Novel Small Molecules as Potential Anti-Cancer Agents
1/1/15 → 12/31/20
Project: Research project
Research and Development of Topical and Intravenous Formulations
6/1/16 → 5/31/17
Project: Other project
Preparation and Purification of Biologically Relevant Natural Products
Rosenberg Integrative Cancer Treatment and Research Institute
1/1/15 → 12/21/15
Project: Research project
Research Output 2002 2019
Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3ß activity
Fultang, N., Illendula, A., Chen, B., Wu, C., Jonnalagadda, S., Baird, N., Klase, Z. & Peethambaran, B., May 1 2019, In : PloS one. 14, 5, e0217789.Research output: Contribution to journal › Article
Open Access
Triple Negative Breast Neoplasms
phosphatidylinositol 3-kinase
Phosphatidylinositol 3-Kinases
breast neoplasms
Modulation
4
Citations
(Scopus)
Benzoboroxoles: Synthesis and applications in medicinal chemistry
Mereddy, G. R., Chakradhar, A., Rutkoski, R. M. & Jonnalagadda, S., Jun 15 2018, In : Journal of Organometallic Chemistry. 865, p. 12-22 11 p.Research output: Contribution to journal › Article
Pharmaceutical Chemistry
chemistry
synthesis
Organic Chemistry
Boronic Acids
Novel methodologies for the synthesis of biologically active Boron-based small molecules
Jonnalagadda, S., Penczuk, B. J., Twomey, K. M., Fishbein, S. H. & Suman, P., Aug 7 2018, Boron in Medicine. World Scientific Publishing Co. Pte Ltd, Vol. 4-4. p. 15-48 34 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Boron
Molecules
9
Citations
(Scopus)
Probing the Binding Pathway of BRACO19 to a Parallel-Stranded Human Telomeric G-Quadruplex Using Molecular Dynamics Binding Simulation with AMBER DNA OL15 and Ligand GAFF2 Force Fields
Machireddy, B., Kalra, G., Jonnalagadda, S., Ramanujachary, K. & Wu, C., Nov 27 2017, In : Journal of Chemical Information and Modeling. 57, 11, p. 2846-2864 19 p.Research output: Contribution to journal › Article
Molecular dynamics
DNA
Ligands
simulation
Intercalation
6
Citations
(Scopus)
Recent Developments on the Synthesis and Applications of Betulin and Betulinic Acid Derivatives as Therapeutic Agents
Jonnalagadda, S., Suman, P., Morgan, D. C. & Seay, J. N., Jan 1 2017, Studies in Natural Products Chemistry. Elsevier B.V., p. 45-84 40 p. (Studies in Natural Products Chemistry; vol. 53).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Betula
Derivatives
Biological Products
Squalene
Therapeutics