Michael O'Leary

  • 1230 Citations
  • 24 h-Index
1982 …2018

Research output per year

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Research Output

  • 1230 Citations
  • 24 h-Index
  • 32 Article
  • 2 Review article
  • 1 Chapter
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Article
2017
14 Scopus citations
2015

Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury

Ritter, D. M., Zemel, B. M., Hala, T. J., O'Leary, M. E., Lepore, A. C. & Covarrubias, M., Jan 21 2015, In : Journal of Neuroscience. 35, 3, p. 1260-1273 14 p.

Research output: Contribution to journalArticle

24 Scopus citations
2 Scopus citations
2014

Modulation of peripheral Na+ channels and neuronal firing by n-butyl-p-aminobenzoate

Thériault, O., Poulin, H., Sculptoreanu, A., De Groat, W. C., O'Leary, M. E. & Chahine, M., Mar 15 2014, In : European Journal of Pharmacology. 727, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Regulation/modulation of sensory neuron sodium channels

Chahine, M. & O’Leary, M. E., Jan 1 2014, In : Handbook of Experimental Pharmacology. 221, p. 111-135 25 p.

Research output: Contribution to journalArticle

28 Scopus citations
2012

Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons

Ho, C., Zhao, J., Malinowski, S., Chahine, M. & O'Leary, M. E., Apr 27 2012, In : Journal of Biological Chemistry. 287, 18, p. 15044-15053 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons

Ritter, D. M., Ho, C., O'Leary, M. E. & Covarrubias, M., Jan 2012, In : Journal of Physiology. 590, 1, p. 145-161 17 p.

Research output: Contribution to journalArticle

30 Scopus citations
2011

Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits

Zhao, J., O'Leary, M. E. & Chahine, M., Aug 2011, In : Journal of Neurophysiology. 106, 2, p. 608-619 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Regulatory role of voltage-gated Na+ channel β subunits in sensory neurons

Chahine, M. & O'Leary, M. E., 2011, In : Frontiers in Pharmacology. 2 NOV, Article 70.

Research output: Contribution to journalArticle

29 Scopus citations

Single-cell analysis of sodium channel expression in dorsal root ganglion neurons

Ho, C. & O'Leary, M. E., Jan 1 2011, In : Molecular and Cellular Neuroscience. 46, 1, p. 159-166 8 p.

Research output: Contribution to journalArticle

98 Scopus citations

Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels

Huang, H., Priori, S. G., Napolitano, C., O'Leary, M. E. & Chahine, M., Jan 1 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 300, 1, p. H288-H299

Research output: Contribution to journalArticle

34 Scopus citations
2007

Lidocaine promotes the trafficking and functional expression of Na v1.8 sodium channels in mammalian cells

Zhao, J., Ziane, R., Chatelier, A., O'Leary, M. E. & Chahine, M., Jul 1 2007, In : Journal of Neurophysiology. 98, 1, p. 467-477 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2005

Inhibition of the A-type K+ channels of dorsal root ganglion neurons by the long-duration anesthetic butamben

Winkelman, D. L. B., Beck, C. L., Ypey, D. L. & O'Leary, M. E., Sep 2005, In : Journal of Pharmacology and Experimental Therapeutics. 314, 3, p. 1177-1186 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
2004

State-dependent trapping of flecainide in the cardiac sodium channel

Ramos, E. & O'Leary, M. E., Oct 1 2004, In : Journal of Physiology. 560, 1, p. 37-49 13 p.

Research output: Contribution to journalArticle

72 Scopus citations
2003

Closing and Inactivation Potentiate the Cocaethylene Inhibition of Cardiac Sodium Channels by Distinct Mechanisms

O'Leary, M. E., Digregorio, M. & Chahine, M., Dec 1 2003, In : Molecular Pharmacology. 64, 6, p. 1575-1585 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain

Beekwilder, J. P., O'Leary, M. E., Van Den Broek, L. P., Van Kempen, G. T. H., Ypey, D. L. & Van Den Berg, R. J., Feb 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 304, 2, p. 531-538 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2002

Cocaine binds to a common site on open and inactivated human heart (Nav 1.5) sodium channels

O'Leary, M. E. & Chahine, M., Jun 15 2002, In : Journal of Physiology. 541, 3, p. 701-716 16 p.

Research output: Contribution to journalArticle

48 Scopus citations

Inhibition of HERG potassium channels by cocaethylene: A metabolite of cocaine and ethanol

O'Leary, M. E., Jan 10 2002, In : Cardiovascular Research. 53, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
2001

Gating properties of Nav1.7 and Nav1.8 peripheral nerve sodium channels

Vijayaragavan, K., O'Leary, M. E. & Chahine, M., Oct 15 2001, In : Journal of Neuroscience. 21, 20, p. 7909-7918 10 p.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Inhibition of human ether-a-go-go potassium channels by cocaine

O'Leary, M. E., Jan 1 2001, In : Molecular Pharmacology. 59, 2, p. 269-277 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
1998
39 Scopus citations
1995

A molecular link between activation and inactivation of sodium channels

O’leary, M. E., Chen, L. Q., Kallen, R. G. & Horn, R., Oct 1 1995, In : Journal of General Physiology. 106, 4, p. 641-658 18 p.

Research output: Contribution to journalArticle

55 Scopus citations
1994

Characterization of d-tubocurarine binding site of Torpedo acetylcholine receptor

O'Leary, M., Filatov, G. N. & White, M. M., Jan 1 1994, In : AM.J.PHYSIOL.. 266, 3 part 1

Research output: Contribution to journalArticle

Characterization of d-tubocurarine binding site of Torpedo acetylcholine receptor

O'Leary, M. E., Filatov, G. N. & White, M. M., 1994, In : American Journal of Physiology - Cell Physiology. 266, 3 35-3, p. C648-C653

Research output: Contribution to journalArticle

50 Scopus citations

Evidence for a direct interaction between internal tetra-alkylammonium cations and the inactivation gate of cardiac sodium channels

O’Leary, M. E., Kallen, R. G. & Horn, R., Sep 1 1994, In : Journal of General Physiology. 104, 3, p. 523-539 17 p.

Research output: Contribution to journalArticle

25 Scopus citations

Internal block of human heart sodium channels by symmetrical tetra-alkylammoniums

O’Leary, M. E. & Horn, R., Sep 1 1994, In : Journal of General Physiology. 104, 3, p. 507-522 16 p.

Research output: Contribution to journalArticle

45 Scopus citations
1992

Mutational analysis of ligand-induced activation of the Torpedo acetylcholine receptor

O'Leary, M. E. & White, M. M., Jan 1 1992, In : Journal of Biological Chemistry. 267, 12, p. 8360-8365 6 p.

Research output: Contribution to journalArticle

81 Scopus citations
1989

Batrachotoxin and α-scorpion toxin stabilize the open state of single voltage-gated sodium channels

O'Leary, M. & Krueger, B. K., Dec 22 1989, In : Molecular Pharmacology. 36, 5, p. 789-795 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
1986
Open Access
93 Scopus citations
1983

Effect of Colchicine on 45Ca and Choline Uptake, and Acetylcholine Release in Rat Brain Synaptosomes

O'Leary, M. & Suszkiw, J. B., Jan 1 1983, In : Journal of Neurochemistry. 40, 4, p. 1192-1195 4 p.

Research output: Contribution to journalArticle

19 Scopus citations
37 Scopus citations
1982
30 Scopus citations