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Dive into the research topics where Jeremy Francis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
- 21 Article
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Oligodendrocyte-targeted adeno-associated virus gene therapy for Canavan disease in children: a phase 1/2 trial
Leone, P., Lober, R. M., Francis, J., Flamini, O., Cecil, K. M., Shera, D. & Janson, C. G., Nov 2025, In: Nature Medicine. 31, 11, p. 3772-3779 8 p.Research output: Contribution to journal › Article › peer-review
5 Link opens in a new tab Scopus citations -
Over-expression of N-acetylaspartate synthase exacerbates pathological energetic deficit and accelerates cognitive decline in the 5xFAD mouse
Francis, J. S., Nguyen, Q., Markov, V. & Leone, P., Feb 2024, In: Journal of Neurochemistry. 168, 2, p. 69-82 14 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations -
Preclinical biodistribution, tropism, and efficacy of oligotropic AAV/Olig001 in a mouse model of congenital white matter disease
Francis, J. S., Markov, V., Wojtas, I. D., Gray, S., McCown, T., Samulski, R. J., Figueroa, M. & Leone, P., Mar 12 2021, In: Molecular Therapy Methods and Clinical Development. 20, p. 520-534 15 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Link opens in a new tab Scopus citations -
N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase
Francis, J. S., Wojtas, I., Markov, V., Gray, S. J., McCown, T. J., Samulski, R. J., Bilaniuk, L. T., Wang, D. J., De Vivo, D. C., Janson, C. G. & Leone, P., Dec 1 2016, In: Neurobiology of Disease. 96, p. 323-334 12 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Link opens in a new tab Scopus citations -
Transcriptional regulation of N-acetylaspartate metabolism in the 5xFAD model of Alzheimer's disease: Evidence for neuron-glia communication during energetic crisis
Zaroff, S., Leone, P., Markov, V. & Francis, J. S., Mar 1 2015, In: Molecular and Cellular Neuroscience. 65, p. 143-152 10 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Link opens in a new tab Scopus citations