Projects per year
Personal profile
Research interests
Research Expertise:
Analytical Chemistry | Liquid Chromatography | Microfluidics
My research background focuses on the fundamental development of liquid chromatography (LC) columns in capillaries and microfluidic devices. LC columns are at the heart of many analytical separation techniques across pharmaceutical, environmental, and biomedical research projects. Early work focused on the physical structure of the packed chromatographic bed inside a fused silica capillary and led to strategies that could be used to pack more efficient columns in capillaries and also miniaturized microfluidic devices. Other interests have included understanding the physical processes beyond bed structure that impact column performance (included extra-column effects and frictional heating) and applying LC and mass spectrometry (MS) instrumentation to solve analytical problems in neuroscience and molecular physiology.
Honors and Awards:
2017 Eastern Michigan University Young Alumnus Award
NIH NRSA Individual Postdoctoral Fellowship Award (F32- EB019800)
HPLC 2013 Csaba Horváth Top Young Scientist Award
Member of:
American Chemical Society (www.acs.org)
California Separation Science Society (www.casss.org)
Chromatography Forum of Delaware Valley (www.cfdv.org)
Education/Academic qualification
Doctor of Philosophy, doctorate
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Network
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Envision Group LLC - Chemical and Pharmaceutical Science Service Agreement
4/1/22 → 7/1/22
Project: Other project
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Development of Separation Devices for Pharmaceutical & Biopharmaceutical Applications
2/28/22 → 2/28/23
Project: Other project
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CAREER: Parallel Two-Dimensional Liquid Chromatography Utilizing Capillary Columns
National Science Foundation (NSF)
1/1/21 → 12/31/25
Project: Other project
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Portable Liquid Chromatography Platform for Diverse Pharmaceutical Applications
5/1/20 → 8/31/22
Project: Other project
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Evaluation of nanospray capillary LC-MS performance for metabolomic analysis in complex biological matrices
Mostafa, M. E., Grinias, J. P. & Edwards, J. L., May 10 2022, In: Journal of Chromatography A. 1670, 462952.Research output: Contribution to journal › Article › peer-review
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A microfluidic chip for on-line derivatization and application to: In vivo neurochemical monitoring
Valenta, A. C., D'Amico, C. I., Dugan, C. E., Grinias, J. P. & Kennedy, R. T., Feb 7 2021, In: Analyst. 146, 3, p. 825-834 10 p.Research output: Contribution to journal › Article › peer-review
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Comparison of design approaches for low-cost sampling mechanisms in open-source chemical instrumentation
Murray, G., Bednarski, S., Hall, M., Foster, S. W., Jin, S. J., Davis, J. J., Xue, W., Constans, E. & Grinias, J. P., Oct 2021, In: HardwareX. 10, e00220.Research output: Contribution to journal › Article › peer-review
Open Access -
Low-cost and open-source strategies for chemical separations
Davis, J. J., Foster, S. W. & Grinias, J. P., Feb 8 2021, In: Journal of Chromatography A. 1638, 461820.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Measurement of optimal flow rate in gradient elution liquid chromatography
Foster, S. W., Wright, N., Grinias, J. P. & Blumberg, L. M., Dec 6 2021, In: Journal of Chromatography A. 1659, 462645.Research output: Contribution to journal › Article › peer-review
1 Scopus citations