James Grinias

  • 318 Citations
  • 9 h-Index

Research output per year

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Personal profile

Research interests

Research Expertise:
Analytical Chemistry | Liquid Chromatography | Microfluidics

My research background focuses on the fundamental development of liquid chromatography (LC) columns in capillaries and microfluidic devices. LC columns are at the heart of many analytical separation techniques across pharmaceutical, environmental, and biomedical research projects. Early work focused on the physical structure of the packed chromatographic bed inside a fused silica capillary and led to strategies that could be used to pack more efficient columns in capillaries and also miniaturized microfluidic devices. Other interests have included understanding the physical processes beyond bed structure that impact column performance (included extra-column effects and frictional heating) and applying LC and mass spectrometry (MS) instrumentation to solve analytical problems in neuroscience and molecular physiology.

Honors and Awards:
2017 Eastern Michigan University Young Alumnus Award
NIH NRSA Individual Postdoctoral Fellowship Award (F32- EB019800)
HPLC 2013 Csaba Horváth Top Young Scientist Award

Member of:
American Chemical Society (www.acs.org)
California Separation Science Society (www.casss.org)
Chromatography Forum of Delaware Valley (www.cfdv.org)

Education/Academic qualification

Doctor of Philosophy, doctorate

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Research Output

  • 318 Citations
  • 9 h-Index
  • 16 Article
  • 3 Review article
  • 1 Editorial

Portable capillary liquid chromatography for pharmaceutical and illicit drug analysis

Foster, S. W., Xie, X., Pham, M., Peaden, P. A., Patil, L. M., Tolley, L. T., Farnsworth, P. B., Tolley, H. D., Lee, M. L. & Grinias, J. P., May 1 2020, In : Journal of Separation Science. 43, 9-10, p. 1623-1627 5 p.

Research output: Contribution to journalArticle

  • 5 Scopus citations
  • Strategies in developing high-throughput liquid chromatography protocols for method qualification of pharmacopeial monographs

    Kresge, G. A., Grosse, S., Zimmer, A., Grinias, K. M., De Pra, M., Wong, J. M. T., Steiner, F. & Grinias, J. P., Aug 1 2020, In : Journal of Separation Science. 43, 15, p. 2964-2970 7 p.

    Research output: Contribution to journalArticle

  • A low-cost, open-source digital stripchart recorder for chromatographic detectors using a Raspberry Pi

    Foster, S. W., Alirangues, M. J., Naese, J. A., Constans, E. & Grinias, J. P., Oct 11 2019, In : Journal of Chromatography A. 1603, p. 396-400 5 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    High-Throughput and Ultrafast Liquid Chromatography

    Kaplitz, A. S., Kresge, G. A., Selover, B., Horvat, L., Franklin, E. G., Godinho, J. M., Grinias, K. M., Foster, S. W., Davis, J. J. & Grinias, J. P., Jan 1 2019, In : Analytical Chemistry.

    Research output: Contribution to journalReview article

    6 Scopus citations